{"id":112312,"date":"2024-10-09T23:12:10","date_gmt":"2024-10-09T16:12:10","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=112312"},"modified":"2024-10-09T23:12:10","modified_gmt":"2024-10-09T16:12:10","slug":"genetic-factors-have-greater-impact-on-lifespan-than-diet-study","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=112312","title":{"rendered":"Genetic factors have greater impact on lifespan than diet: study"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>Who moved their cheese?<\/p>\n<p><a href=\"https:\/\/www.eurekalert.org\/news-releases\/1060191\" target=\"_blank\" rel=\"noreferrer noopener\">A pivotal new study<\/a> that subjected mice to a variety of diets found that genetic factors had a far greater effect on their lifespan than eating habits.<\/p>\n<p>\u201cIf you want to live a long time, there are things you can control within your lifetime such as diet, but really what you want is a very old grandmother,\u201d said study leader <a href=\"https:\/\/www.jax.org\/research-and-faculty\/faculty\/gary-churchill\" target=\"_blank\" rel=\"noreferrer noopener\">Gary Churchill<\/a> of Jackson Laboratory, a biomedical research institution.<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>Intermittent fasting, which restricts eating to certain times, represented two of the diets tested in the new study. <span class=\"credit\">PheelingsMedia \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<p>For the research, nearly 1,000 genetically distinct mice were assigned one of five diets:<\/p>\n<ul>\n<li>Eat any amount of food at any time<\/li>\n<li>Only consume 60% of their baseline calories each day<\/li>\n<li>Only consume 80% of their baseline calories each day<\/li>\n<li>Can\u2019t eat one day each week, could chow down as much as they want the other days<\/li>\n<li>Can\u2019t eat for two consecutive days each week, could scarf as much as they want the other days<\/li>\n<\/ul>\n<aside class=\"single__inline-module aligncenter wp-block-nypost-editor-primary-tag\">\n<\/aside>\n<aside class=\"single__inline-module alignleft\">\n\t<\/aside>\n<p>The mice were given periodic blood tests as they were evaluated for the rest of their lives.<\/p>\n<p>Mice on the unrestricted diet lived an average of 25 months while those on the <a href=\"https:\/\/nypost.com\/2024\/09\/30\/lifestyle\/metabolic-syndrome-patients-may-benefit-from-intermittent-fasting-study\/\">intermittent fasting<\/a> diets lived for about 28 months.<\/p>\n<p>The mice that ate 80% of their baseline calories lived around 30 months while those that consumed 60% of baseline lived for 34 months.<\/p>\n<p>Lifespan ranges varied within each group \u2014 for example, the mice that consumed the fewest calories lived anywhere from a few months to four and a half years.<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>The researchers determined that diets very low in calories generally extended the mice\u2019s lifespan regardless of their amount of body fat or their blood glucose levels. <span class=\"credit\">RasaBasa \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<aside class=\"single__inline-module alignleft\">\n\t<\/aside>\n<p>The researchers determined that diets very low in calories generally extended the mice\u2019s lifespan regardless of their amount of body fat or their blood glucose levels.<\/p>\n<p>However, the study authors were surprised to see that the mice that lived the longest on the restrictive diets lost the least amount of weight \u2014 despite eating less.<\/p>\n<p>Mice that lost the most weight on these diets tended to have low energy, weakened immune and reproductive systems and shorter lives.<\/p>\n<p>\u201cWhile caloric restriction is generally good for lifespan, our data show that losing weight on caloric restriction is actually bad for lifespan,\u201d Churchill explained. \u201cSo when we look at human trials of longevity drugs and see that people are losing weight and have better metabolic profiles, it turns out that might not be a good marker of their future lifespan at all.\u201d<\/p>\n<figure class=\"nyp-slideshow-modal-image wp-block-image aligncenter size-large\"><figcaption>Genetic features, yet to be identified, play a significant role in how diets affect a person\u2019s health trajectory, the researchers said. <span class=\"credit\">Echelon IMG \u2013 stock.adobe.com<\/span><\/figcaption><\/figure>\n<aside class=\"single__inline-module alignleft\">\n\t<\/aside>\n<p>Churchill\u2019s team pinpointed genetically encoded resilience as a key factor in lifespan, noting that the mice that naturally maintained their weight, body fat percentage and immune cell health even in the face of stress and caloric restriction, as well as the mice that did not lose body fat late in life, survived the longest.<\/p>\n<p>Churchill said the results, <a href=\"https:\/\/dx.doi.org\/10.1038\/s41586-024-08026-3\" target=\"_blank\" rel=\"noreferrer noopener\">published Wednesday in Nature<\/a>, \u201csuggest that a more moderate level of calorie restriction might be the way to balance long-term health and lifespan.\u201d<\/p>\n<p>The research team found that immune system health and traits related to red blood cells were more clearly linked to lifespan than weight, body fat percentages, blood glucose levels and body temperature.<\/p>\n<p>Genetic features, yet to be identified, play a significant role in how diets affect a person\u2019s health trajectory, the researchers said.<\/p>\n<div class=\"single__inline-module inline-module inline-module--newsletter aligncenter aligncenter wp-block-nypost-editor-newsletter\">\n<div class=\"inline-module__inner\">\n<div class=\"inline-module__title-wrapper\">\n<div class=\"inline-module__unsubmitted-title-wrapper\">\n<h3 class=\"inline-module__title headline headline--combo-sm-md\">\n\t\t\t\t\tGet the latest breakthroughs in medicine, diet &amp; nutrition tips and more.\t\t\t\t<\/h3>\n<p class=\"inline-module__cta\">\n\t\t\t\t\tSubscribe to our weekly Post Care newsletter!\t\t\t\t<\/p>\n<\/p><\/div>\n<p><h3 class=\"inline-module__title headline headline--combo-sm-md\">\n\t\t\t\t\tThanks for signing up!\t\t\t\t<\/h3>\n<\/p><\/div>\n<\/p><\/div>\n<\/div>\n<p>The study comes as <a href=\"https:\/\/nypost.com\/2024\/06\/02\/lifestyle\/how-intermittent-fasting-protein-pacing-can-lead-to-weight-loss\/\">intermittent fasting<\/a> and <a href=\"https:\/\/nypost.com\/2024\/09\/13\/lifestyle\/female-wegovy-users-may-have-greatest-weight-loss\/\">extreme weight loss<\/a> through weekly injections like Ozempic have become popular to stave off obesity and <a href=\"https:\/\/nypost.com\/2024\/07\/29\/lifestyle\/cut-sugar-from-your-diet-to-lower-your-biological-age-study\/\">possibly slow aging<\/a>.<\/p>\n<p>Emily Feivor, a registered dietitian at <a href=\"https:\/\/foresthills.northwell.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Northwell Long Island Jewish Forest Hills Hospital<\/a>, said more than one lifestyle intervention \u2014 not just healthy eating \u2014 is necessary for good health.<\/p>\n<p>\u201cExercise and a balanced diet are arguably supreme when talking above improving overall health,\u201d Feivor, who is not involved in the new research, told The Post. \u201cCalorie restriction may not be for everyone as it could increase the risk for malnutrition and other health issues and should be discussed with your medical provider.\u201d<\/p>\n<\/p><\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/nypost.com\/2024\/10\/09\/lifestyle\/genetic-factors-have-greater-impact-on-lifespan-than-diet\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Who moved their cheese? A pivotal new study that subjected mice to a variety of diets found that genetic factors had a far greater effect on their lifespan than eating &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=112312\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-112312","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/112312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=112312"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/112312\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=112312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=112312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=112312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}