{"id":112470,"date":"2024-10-10T09:21:56","date_gmt":"2024-10-10T02:21:56","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=112470"},"modified":"2024-10-10T09:21:56","modified_gmt":"2024-10-10T02:21:56","slug":"your-blood-type-affects-your-risk-of-an-early-stroke-scientists-discover-sciencealert","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=112470","title":{"rendered":"Your Blood Type Affects Your Risk of an Early Stroke, Scientists Discover : ScienceAlert"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>People with one of the type A blood groups are more likely to have a stroke before the age of 60 compared with people with other blood types, research shows.<\/p>\n<p><a href=\"https:\/\/www.science.org.au\/curious\/people-medicine\/understanding-different-blood-types\">Blood types<\/a> describe the rich variety of chemicals displayed on the surface of our red blood cells.<\/p>\n<p>Among the most familiar are those named A and B, which can be present together as AB, individually as A or B, or not present at all, as O.<\/p>\n<figure id=\"attachment_140271\" aria-describedby=\"caption-attachment-140271\" style=\"width: 642px\" class=\"wp-caption alignnone\"><img decoding=\"async\" src=\"https:\/\/www.sciencealert.com\/images\/2024\/10\/MajorBloodTypesChart642.jpg\" alt=\"Diagram of ABO blood groups and the IgM antibodies present in each.\" width=\"642\" height=\"413\" class=\"size-full wp-image-140271\" srcset=\"https:\/\/www.sciencealert.com\/images\/2024\/10\/MajorBloodTypesChart642.jpg 642w, https:\/\/www.sciencealert.com\/images\/2024\/10\/MajorBloodTypesChart642-600x386.jpg 600w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" loading=\"lazy\"\/><figcaption id=\"caption-attachment-140271\" class=\"wp-caption-text\">Blood type is partly determined by the ABO blood group antigens present on red blood cells. (<a href=\"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/3\/32\/ABO_blood_type.svg\">InvictaHOG\/Public Domain\/Wikimedia Commons<\/a>)<\/figcaption><\/figure>\n<p>Even within these major blood types, there are subtle variations arising from mutations in the genes responsible.<\/p>\n<p>In a study published in 2022, genomics researchers uncovered a clear relationship between the gene for the A1 subgroup and early onset stroke.<\/p>\n<p>Researchers compiled data from 48 genetic studies, which included roughly 17,000 people with a stroke and nearly 600,000 non-stroke controls. All participants were between 18 and 59 years of age.<\/p>\n<p>A genome-wide search revealed two locations strongly associated with an earlier risk of stroke. One coincided with the spot where genes for blood type sit.<\/p>\n<p>A second analysis of specific types of blood-type gene then found people whose genome coded for a variation of the A group had a 16 percent higher chance of a stroke before the age 60, compared with a population of other blood types.<\/p>\n<p>For those with a gene for group O1, the risk was lower by 12 percent.<\/p>\n<p>The researchers noted, however, that the additional risk of stroke in people with type A blood is small, so there is no need for extra vigilance or screening in this group.<\/p>\n<p>&#8220;We still don&#8217;t know why blood type A would confer a higher risk,&#8221; <a href=\"https:\/\/www.eurekalert.org\/news-releases\/963353\">said<\/a> senior author and vascular neurologist Steven Kittner from the University of Maryland.<\/p>\n<p>&#8220;But it likely has something to do with blood-clotting factors like platelets and cells that line the blood vessels as well as other circulating proteins, all of which play a role in the development of blood clots.&#8221;<\/p>\n<p>While the study findings may seem alarming \u2013 that blood type could change early stroke risk \u2013 let&#8217;s put these results into context.<\/p>\n<p>Each year in the US just under 800,000 individuals experience a stroke. Most of these events \u2013 around <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6535078\/\">three out of every four<\/a> \u2013 occur in people 65 years and older, with risks doubling every decade after the age of 55.<\/p>\n<p>Also, the people included in the study lived in North America, Europe, Japan, Pakistan, and Australia, with people of non-European ancestry only making up 35 percent of participants. Future studies with a more diverse sample could help clarify the significance of the results.<\/p>\n<p>&#8220;We clearly need more follow-up studies to clarify the mechanisms of increased stroke risk,&#8221; Kittner <a href=\"https:\/\/www.eurekalert.org\/news-releases\/963353\">said<\/a>.<\/p>\n<p>Another key finding of the study came from comparing people who had a stroke before the age of 60 to those that had a stroke after the age of 60.<\/p>\n<p>For this, the researchers used a dataset of about 9,300 people over the age of 60 who had a stroke, and some 25,000 controls over the age of 60 who didn&#8217;t have a stroke.<\/p>\n<p>They found that the increased risk of stroke in the type A blood group became insignificant in the late-onset stroke group, suggesting that strokes that happen early in life may have a different mechanism compared to those that occur later on.<\/p>\n<p><iframe loading=\"lazy\" title=\"Learn About the Types of Strokes\" width=\"1170\" height=\"658\" src=\"https:\/\/www.youtube.com\/embed\/UJ5aO4KmQ8M?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe> frameborder=&#8221;0\u2033 allow=&#8221;accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share&#8221; referrerpolicy=&#8221;strict-origin-when-cross-origin&#8221; allowfullscreen&gt;<\/iframe><\/p>\n<p>Strokes in younger people are less likely to be caused by a build-up of fatty deposits in the arteries (a process called atherosclerosis) and more likely to be caused by factors to do with clot formation, the authors <a href=\"https:\/\/n.neurology.org\/content\/99\/16\/e1738\">said<\/a>.<\/p>\n<p>The study also found that people with type B blood were around 11 percent more likely to have a stroke compared to non-stroke controls regardless of their age.<\/p>\n<p><a href=\"https:\/\/doi.org\/10.1038\/ng.784\">Previous studies<\/a> suggest that the part of the genome that codes for blood type, called the &#8216;ABO locus&#8217;, is associated with coronary artery calcification, which restricts blood flow, and heart attack.<\/p>\n<p>The genetic sequence for A and B blood types have also been associated with a slightly higher risk of blood clots in veins, called venous thrombosis.<\/p>\n<p>This paper was published in <em><a href=\"https:\/\/n.neurology.org\/content\/early\/2022\/08\/31\/WNL.0000000000201006\">Neurology<\/a>.<\/em><\/p>\n<p><em>An earlier version of this article was published in September 2022.<\/em><\/p>\n<\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.sciencealert.com\/your-blood-type-affects-your-risk-of-an-early-stroke-scientists-discover\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>People with one of the type A blood groups are more likely to have a stroke before the age of 60 compared with people with other blood types, research shows. &hellip; 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