{"id":112681,"date":"2024-10-10T22:34:47","date_gmt":"2024-10-10T15:34:47","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=112681"},"modified":"2024-10-10T22:34:47","modified_gmt":"2024-10-10T15:34:47","slug":"14-skinny-genes-linked-to-enhanced-weight-loss","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=112681","title":{"rendered":"14 &#8220;Skinny&#8221; Genes Linked to Enhanced Weight Loss"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p><strong>Summary: <\/strong>A recent study identifies 14 genes linked to enhanced weight loss when combined with moderate exercise, such as running for 30 minutes three times a week. Participants with the highest number of these \u201cskinny genes\u201d lost up to 5kg over eight weeks, while others lost about 2kg.<\/p>\n<p>One gene, PARGC1A, emerged as particularly influential, accounting for 62% of weight lost in participants, with the rest attributed to exercise and lifestyle factors. The study emphasizes that while genetics play a role, lifestyle changes are essential for optimal results.<\/p>\n<p>The findings could pave the way for personalized health and fitness interventions based on genetic profiles. This research supports the need for a balanced approach, combining genetics with exercise and diet for best outcomes.<\/p>\n<p><strong>Key Facts<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>Participants with more \u201cskinny genes\u201d lost up to 5kg over eight weeks.<\/li>\n<li>PARGC1A gene alone influenced 62% of weight loss in those with it.<\/li>\n<li>Exercise and lifestyle still accounted for 37% of total weight loss.<\/li>\n<\/ul>\n<p><strong>Source: <\/strong>University of Essex<\/p>\n<p><strong>The secret to losing weight could all be down to a combination of 14 \u2018skinny genes\u2019, a new study has found.\u00a0\u00a0<\/strong><\/p>\n<p>University of Essex researchers discovered they helped people drop twice as much weight when they ran for half an hour three times a week.\u00a0\u00a0<\/p>\n<p>The team \u2013 led by Dr Henry Chung, from the School of Sport, Rehabilitation and Exercise Sciences \u2013 found those with more of the genes slimmed the most across eight weeks.\u00a0\u00a0<\/p>\n<p>People with the most markers lost up to 5kg during the study and people without them dropped an average of 2kg.\u00a0\u00a0<\/p>\n<figure class=\"wp-block-image size-full\"><picture fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-105287\"><source type=\"image\/webp\" srcset=\"https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience.jpg.webp 1200w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-300x200.jpg.webp 300w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-770x513.jpg.webp 770w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-1155x770.jpg.webp 1155w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-370x247.jpg.webp 370w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-293x195.jpg.webp 293w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-150x100.jpg.webp 150w\" sizes=\"(max-width: 1200px) 100vw, 1200px\"\/><img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"799\" src=\"https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience.jpg\" alt=\"This shows a woman surrounded by DNA.\" srcset=\"https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience.jpg 1200w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-300x200.jpg 300w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-770x513.jpg 770w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-1155x770.jpg 1155w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-370x247.jpg 370w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-293x195.jpg 293w, https:\/\/neurosciencenews.com\/files\/2024\/10\/genetics-weight-loss-neuroscience-150x100.jpg 150w\" sizes=\"(max-width: 1200px) 100vw, 1200px\"\/> <\/picture><figcaption class=\"wp-element-caption\">They were instructed to follow their normal diets and lifestyle habits, not do any other training, and were weighed before and after the study.  Credit: Neuroscience News<\/figcaption><\/figure>\n<p>The study found the PARGC1A gene that encodes PGC-1-a was key to weight loss and present in the participants who lost the most weight.\u00a0<\/p>\n<p>With the research showing that 62 per cent of the dropped kilograms were linked to the gene and 37 per cent linked to exercise and lifestyle factors.\u00a0<\/p>\n<p>Despite the results, Dr Chung said lifestyle factors and diet are still vital for slimming down.\u00a0\u00a0<\/p>\n<p>Dr Chung said: \u201cThis study highlighted some important genes associated with taking inches off the jeans, but it\u2019s important to remember that the genes will do nothing without exercise and lifestyle changes as they are all interlinked.\u00a0\u00a0<\/p>\n<p>\u201cWithout intervention, they won\u2019t show their true potential and then it doesn\u2019t matter what genes you have!\u00a0<\/p>\n<p>\u201cAway from weight loss exercise has so many benefits \u2013 ranging from mental health to cardiovascular fitness \u2013 so I\u2019d advise everyone to keep on training even if they aren\u2019t seeing the difference on the scales.\u201d\u00a0<\/p>\n<p>The study followed 38 people all aged between 20 and 40 years old.\u00a0\u00a0<\/p>\n<p>They were instructed to follow their normal diets and lifestyle habits, not do any other training, and were weighed before and after the study.\u00a0<\/p>\n<p>The paper, published in\u00a0<em>Research Quarterly for Exercise and Sport,<\/em>\u00a0builds on Dr Chung\u2019s previous study which showed running performance was also linked to genetics.\u00a0\u00a0<\/p>\n<p>He hopes the research will allow governments, companies, and individuals to better tailor health interventions.\u00a0\u00a0<\/p>\n<p>\u201cIf we can better understand someone\u2019s specific genetic profile, hopefully, this will translate to better and more successful interventions for improving health outcomes\u201d added Dr Chung.\u00a0<\/p>\n<h2 class=\"wp-block-heading\">About this genetics research news<\/h2>\n<p class=\"has-background\" style=\"background-color:#ffffe8\"><strong>Author: <\/strong><a href=\"http:\/\/neurosciencenews.com\/cdn-cgi\/l\/email-protection#8be8e4e6e6f8cbeef8f8eef3a5eae8a5fee0\" target=\"_blank\" rel=\"noreferrer noopener\">Ben Hall<\/a><br \/><strong>Source: <\/strong><a href=\"https:\/\/essex.ac.uk\" target=\"_blank\" rel=\"noreferrer noopener\">University of Essex<\/a><br \/><strong>Contact: <\/strong>Ben Hall \u2013 University of Essex<br \/><strong>Image: <\/strong>The image is credited to Neuroscience News<\/p>\n<p class=\"has-background\" style=\"background-color:#ffffe8\"><strong>Original Research: <\/strong>Open access.<br \/>\u201c<a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/02701367.2024.2404981\" target=\"_blank\" rel=\"noreferrer noopener\">Genotypic Variations Associated with Changes in Body Mass in Response to Endurance Training<\/a>\u201d by Henry Chung et al. <em>Research Quarterly for Exercise and Sport<\/em><\/p>\n<hr class=\"wp-block-separator has-text-color has-pale-cyan-blue-color has-alpha-channel-opacity has-pale-cyan-blue-background-color has-background\"\/>\n<p><strong>Abstract<\/strong><\/p>\n<p><strong>Genotypic Variations Associated with Changes in Body Mass in Response to Endurance Training<\/strong><\/p>\n<p>This study investigates the extent to which different genotypes can explain changes in body mass following an 8-week running program, in a UK population.<\/p>\n<p>Participants were randomly assigned to either a training (<em>n<\/em>\u2009=\u200917) or control group (<em>n<\/em>\u2009=\u200921). Participants\u2019 diets were not altered, only the exercise regime was manipulated to isolate effects.<\/p>\n<p>The exercise group completed a periodized running program consisting of 20\u201330\u00a0min, over an agreed route, three times per-week, whilst the control groups refrained from daily exercise. Participants were screened at the end of the study for 1,000 gene variants using a DNA test kit.<\/p>\n<p>Results demonstrated a significant reduction in body mass, within the exercise, compared to the control group (<em>p<\/em>\u2009=\u2009.002). This reduction in body mass varied significantly (<em>p<\/em>\u2009=\u2009.024) between individuals within the exercise group.<\/p>\n<p>Moreover, genetic analysis identified 17 single nucleotide polymorphisms (SNPs) associated with this variation (r<sup>2<\/sup>\u2009=\u2009.74;\u00a0<em>p<\/em>\u2009&lt;\u2009.001).<\/p>\n<p>These findings indicate that individuals with specific alleles are better predisposed to weight-management, compared to their counterparts, following an exercise program.<\/p>\n<p>This study helps to bridge the gap between population health and exercise science and can inform research in the application of genetics to help develop individually tailored health interventions.<\/p>\n<p> <!-- Form created by Optin Forms plugin by WPKube: create beautiful optin forms with ease! --> <!-- https:\/\/wpkube.com\/ --><!--optinforms-form5-container--> <!-- \/ Optin Forms --> <\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/neurosciencenews.com\/skinny-gene-weight-27828\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summary: A recent study identifies 14 genes linked to enhanced weight loss when combined with moderate exercise, such as running for 30 minutes three times a week. Participants with the &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=112681\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-112681","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/112681","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=112681"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/112681\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=112681"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=112681"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=112681"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}