{"id":114132,"date":"2024-10-14T19:06:25","date_gmt":"2024-10-14T12:06:25","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=114132"},"modified":"2024-10-14T19:06:25","modified_gmt":"2024-10-14T12:06:25","slug":"drinking-caffeine-may-reduce-alzheimers-clumps-in-the-brain-study-finds-sciencealert","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=114132","title":{"rendered":"Drinking Caffeine May Reduce Alzheimer&#8217;s Clumps in The Brain, Study Finds : ScienceAlert"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>Whether in your morning espresso, followed by an English breakfast with your toast, or a quick cup of instant between meetings, a moderate amount of <a href=\"https:\/\/sciencealert.com\/how-does-caffeine-wake-you-up\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73115\" data-postid=\"140416\" rel=\"nofollow noopener\" target=\"_self\">caffeine<\/a> throughout the day<a href=\"https:\/\/www.sciencealert.com\/some-coffee-and-tea-drinkers-could-be-lowering-their-risk-of-dementia\"> is associated with<\/a> a reduced risk of worsening dementia.<\/p>\n<p>A new study has now confirmed a link between caffeine intake and spinal fluid markers for <a href=\"https:\/\/www.sciencealert.com\/go\/IaO\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73015\" data-postid=\"140416\" rel=\"nofollow noopener\" target=\"_self\">Alzheimer&#8217;s<\/a> disease.<\/p>\n<p>Most previous research has focused on observational studies or meta-analyses on the consumption of tea and <a href=\"https:\/\/sciencealert.com\/how-does-caffeine-wake-you-up\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73115\" data-postid=\"140416\" rel=\"nofollow noopener\" target=\"_self\">coffee<\/a>, with comparatively little insight gathered on the<a href=\"https:\/\/www.sciencealert.com\/italian-study-shows-how-espressos-keep-alzheimers-protein-clumps-in-check\"> biological changes caffeine delivers<\/a>.<\/p>\n<p>A team in France looked at data from a prospective study that evaluated patients with mild cognitive impairment or Alzheimer&#8217;s between 2010 and 2015.<\/p>\n<p>Their analysis of 263 participants aged over 70 included a baseline clinical evaluation and a detailed survey of consumption of foods and beverages such as coffee, chocolate, tea, and soda to assess the amount of caffeine absorbed by their bodies each day. Volunteers also had <a href=\"https:\/\/sciencealert.com\/magnetic-resonance-imaging\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73063\" data-postid=\"140416\" rel=\"nofollow noopener\" target=\"_self\">MRI<\/a> scans taken, and provided samples of blood and cerebrospinal fluid (CSF).<\/p>\n<p>Those who consumed an average of just over 200 milligrams of caffeine per day were grouped into a &#8216;low&#8217; caffeine sample, with those who drank more considered to be higher caffeine consumers.<\/p>\n<p>The difference amounts to a can of energy drink or a cup or two of coffee a day, versus several cans or cups respectively \u2013 a distinction that could impact the pathology responsible for dementia.<\/p>\n<p>The team found lower caffeine consumption correlated with a higher risk of mild cognitive decline with impaired memory, compared with higher caffeine consumption.<\/p>\n<p>In fact, those in the low-caffeine consumption group were nearly 2.5 times more likely to have a diagnosis of mild cognitive impairment with impaired memory or Alzheimer&#8217;s.<\/p>\n<p>A closer look at proteins in the participants&#8217; spinal fluid also revealed significant differences in ratios and concentrations of specific forms of beta-amyloid proteins. Those who drank less caffeine tended to have lower concentrations of a soluble form <a href=\"https:\/\/content.iospress.com\/articles\/journal-of-alzheimers-disease\/jad170784\">called A\u03b242<\/a>, with reduced ratios of A\u03b242 with another form called A\u03b240.<\/p>\n<p>They also had a reduced ratio between A\u03b242 and a form of tau protein called <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mco2.1\">ptau-181<\/a> than those who drank higher levels of caffeine.<\/p>\n<p>Taken together, these specific protein levels in the CSF among those who consumed less caffeine signify increased clumping of beta-amyloid proteins in the brain, which is a biological hallmark of the neurodegeneration responsible for Alzheimer&#8217;s symptoms.<\/p>\n<p>Oddly, the amount of caffeine consumed didn&#8217;t seem to affect levels of tau protein, <a href=\"https:\/\/www.sciencealert.com\/breakthrough-alzheimers-drug-targets-key-hotspots-to-suppress-toxic-tangles\">which are also known<\/a> to increasingly accumulate in brain tissue as Alzheimer&#8217;s symptoms worsen.<\/p>\n<p>Research on caffeine&#8217;s effects on tau in the brain has been limited, though <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s12031-010-9444-8\">one laboratory study<\/a> has indicated it could reduce the chemical activity that causes the protein to &#8216;tangle&#8217; in toxic clumps. Yet whether this occurs in cases of Alzheimer&#8217;s isn&#8217;t clear.<\/p>\n<p>This latest investigation is based on a mere snapshot of caffeine habits among a few hundred older individuals, so says little about how a morning coffee throughout your youth or middle age might affect the emergence of dementia later.<\/p>\n<p>Consideration needs to be taken for when and how caffeine is consumed. Drinking it <a href=\"https:\/\/www.sciencealert.com\/theres-one-critical-thing-we-can-do-to-keep-alzheimers-symptoms-at-bay\">late in the day<\/a> could impact sleep, for example, which also seems to impact long-term neurological functioning. Relying heavily on chocolate and energy drinks comes with an added load of sugar, which <a href=\"https:\/\/www.sciencealert.com\/evidence-mysterious-link-between-sugar-alzheimer-s-cognitive-decline-diabetes\">also puts cognitive health at risk<\/a>.<\/p>\n<p>Taken together with the growing pile of research on the relationship between caffeine and <a href=\"https:\/\/www.sciencealert.com\/7-ways-that-drinking-coffee-can-actually-be-good-for-you\">health in general<\/a>, however, it&#8217;s a solid bet that your <a href=\"https:\/\/www.healthline.com\/nutrition\/caffeine-in-tea-vs-coffee\">morning Earl Gray<\/a>, midday latte, and small <a href=\"https:\/\/www.healthline.com\/health\/does-chocolate-have-caffeine\">afternoon chocolate snack<\/a> might play a role in keeping your body working for many years to come.<\/p>\n<p>This research was published in <em><a href=\"https:\/\/doi.org\/10.1002\/alz.14169\">Alzheimer&#8217;s &amp; Dementia<\/a><\/em>.<\/p>\n<\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.sciencealert.com\/drinking-caffeine-may-reduce-alzheimers-clumps-in-the-brain-study-finds\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Whether in your morning espresso, followed by an English breakfast with your toast, or a quick cup of instant between meetings, a moderate amount of caffeine throughout the day is &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=114132\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-114132","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/114132","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=114132"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/114132\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=114132"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=114132"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=114132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}