{"id":116846,"date":"2024-10-21T22:57:01","date_gmt":"2024-10-21T15:57:01","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=116846"},"modified":"2024-10-21T22:57:01","modified_gmt":"2024-10-21T15:57:01","slug":"people-with-depression-could-administer-brain-stimulation-at-home-trial-shows-science","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=116846","title":{"rendered":"People with depression could administer brain stimulation at home, trial shows | Science"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p class=\"dcr-1eu361v\">People with major depression could alleviate their symptoms by self-administering a form of electrical brain stimulation at home, according to a clinical trial of the therapy.<\/p>\n<p class=\"dcr-1eu361v\">Patients who took a 10-week course of the treatment were about twice as likely to see their depression go into remission than those in a control group who performed the same procedure with the current switched off.<\/p>\n<p class=\"dcr-1eu361v\">The findings suggest that people with depression could receive beneficial brain stimulation without having to attend a clinic and that the treatment could become an effective alternative for those who do not want, or do not respond to, more traditional therapies.<\/p>\n<p class=\"dcr-1eu361v\">\u201cThis is a potential first line treatment for depression,\u201d said Cynthia Fu, a professor of affective neuroscience and psychotherapy at King\u2019s College London and senior author on the study.<\/p>\n<p class=\"dcr-1eu361v\">\u201cIt can also be used for people whose depression hasn\u2019t improved with antidepressant medication, for people who don\u2019t like antidepressant medication, or who don\u2019t want psychotherapy.\u201d<\/p>\n<p class=\"dcr-1eu361v\">For the phase two trial, 174 people with major depressive disorder were given a headset to deliver what is known as transcranial direct current stimulation (tDCS). The headset, produced by Flow <a href=\"https:\/\/www.theguardian.com\/science\/neuroscience\" data-link-name=\"in body link\" data-component=\"auto-linked-tag\">Neuroscience<\/a>, which also funded the trial, contains two electrodes that apply a weak current of up to 2 milliamps to the forehead.<\/p>\n<p class=\"dcr-1eu361v\">The 10-week course was supervised in real-time over video conference calls, starting with five 30-minute sessions a week for three weeks, followed by three 30-minute sessions a week for the next seven weeks.<\/p>\n<p class=\"dcr-1eu361v\">While half the participants received electrical brain stimulation as expected, the other half unknowingly had \u201cinactive\u201d therapy, where the device delivered a brief, weak current at the start and finish of the session, but was otherwise not providing any stimulation.<\/p>\n<p class=\"dcr-1eu361v\">Writing in the journal <a href=\"https:\/\/www.nature.com\/articles\/s41591-024-03305-y\" data-link-name=\"in body link\">Nature Medicine<\/a>, the researchers report that depression improved in both groups over the 10-week course, according to their scores on standard depression scales.<\/p>\n<p class=\"dcr-1eu361v\">But those who had active brain stimulation improved most. The remission rate in the brain stimulation group was 44.9% compared with 21.8% in the inactive control group.<\/p>\n<p class=\"dcr-1eu361v\">An estimated 5% of adults globally live with depression. The most common treatments are antidepressants and psychological therapies but more than a third of people with major depressive disorder do not reach full clinical remission.<\/p>\n<p class=\"dcr-1eu361v\">tDCS makes neurons in frontal regions of the brain fire more readily, an effect that is thought to have a beneficial impact on the broader brain network affected by depression.<\/p>\n<p class=\"dcr-1eu361v\">\u201cWe did see a placebo effect, with people who were receiving the inactive treatment showing an improvement,\u201d Fu told the Guardian. \u201cBut there were more people in the active treatment arm whose depression improved than in the inactive treatment arm.\u201d<\/p>\n<p class=\"dcr-1eu361v\">tDCS is already used to treat conditions such as psychosis and eating disorders, and trials so far suggest the procedure is safe. The current delivered to the brain is at least 400 times weaker than that used in electroconvulsive therapy, which induces a generalised seizure in the brain. To reduce any risks from prolonged stimulation, the device shuts off after 30 minutes.<\/p>\n<p class=\"dcr-1eu361v\">\u201cAlthough tDCS for depression has been in Nice [National Institute for <a href=\"https:\/\/www.theguardian.com\/society\/health\" data-link-name=\"in body link\" data-component=\"auto-linked-tag\">Health<\/a> and Care Excellence] guidelines since 2015 and is considered \u2018safe\u2019, uncertainties about its efficacy remain,\u201d said Myles Jones, a senior lecturer in psychology at the University of Sheffield, who was not involved in the study.<\/p>\n<p class=\"dcr-1eu361v\">\u201cThis study demonstrates that repeated home use of tDCS is associated with a reduction in a key depression measure.\u201d<\/p>\n<p class=\"dcr-1eu361v\">He added: \u201cAlthough single doses of tDCS have proved equivocal in changing neural activity and cognitive performance, prolonged use over days or weeks has been shown to be clinically effective in depression, tinnitus and a range of conditions.\u201d<\/p>\n<\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.theguardian.com\/science\/2024\/oct\/21\/people-with-depression-could-administer-brain-stimulation-at-home-trial-shows\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>People with major depression could alleviate their symptoms by self-administering a form of electrical brain stimulation at home, according to a clinical trial of the therapy. Patients who took a &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=116846\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-116846","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/116846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=116846"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/116846\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=116846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=116846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=116846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}