{"id":121672,"date":"2024-11-03T18:04:45","date_gmt":"2024-11-03T11:04:45","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=121672"},"modified":"2024-11-03T18:04:45","modified_gmt":"2024-11-03T11:04:45","slug":"vitamin-d-deficiency-can-trigger-autoimmune-conditions-heres-why-sciencealert","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=121672","title":{"rendered":"Vitamin D Deficiency Can Trigger Autoimmune Conditions. Here&#8217;s Why. : ScienceAlert"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p><a href=\"https:\/\/en.wikipedia.org\/wiki\/Vitamin_D\">Vitamin D<\/a> is important to our <a href=\"https:\/\/www.sciencealert.com\/massive-review-shows-vitamin-d-really-does-seem-to-ease-depressive-symptoms\">overall health<\/a>, and now scientists have made some notable discoveries about how deficiency early in life can trigger problems with the body&#8217;s immune system.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Researchers from McGill University in Canada used a combination of analysis techniques to take a close look at mice genetically engineered to not produce  <a href=\"https:\/\/www.sciencealert.com\/what-are-vitamins-and-do-we-really-need-to-take-them\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73116\" data-postid=\"141335\" rel=\"nofollow noopener\" target=\"_self\">vitamin<\/a> D naturally.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>They found that the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Thymus\">thymus<\/a> \u2013 a small organ that trains our immune system \u2013 ages faster in these mice, allowing self-attacking immune cells to run rampant.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>We know the thymus has <a href=\"https:\/\/www.nature.com\/articles\/nri3667\">an important role<\/a> in educating the T cell defense force in our bodies not to attack healthy cells, and we also know vitamin D <a href=\"https:\/\/academic.oup.com\/jbmr\/article-abstract\/34\/11\/1985\/7605994\">is closely linked<\/a> to this process too. Now, those biological relationships are much clearer.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;Our findings bring new clarity to this connection and could lead to new strategies for preventing autoimmune diseases,&#8221; <a href=\"https:\/\/www.mcgill.ca\/newsroom\/channels\/news\/how-vitamin-d-deficiency-can-lead-autoimmune-diseases-360580\">says<\/a> McGill University physiologist John White.<\/p>\n<figure id=\"attachment_141338\" aria-describedby=\"caption-attachment-141338\" style=\"width: 642px\" class=\"wp-caption alignnone\"><img decoding=\"async\" src=\"https:\/\/www.sciencealert.com\/images\/2024\/10\/ProteinLevel.jpg\" alt=\"Protein level\" width=\"642\" height=\"374\" class=\"wp-image-141338 size-full\" srcset=\"https:\/\/www.sciencealert.com\/images\/2024\/10\/ProteinLevel.jpg 642w, https:\/\/www.sciencealert.com\/images\/2024\/10\/ProteinLevel-600x350.jpg 600w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" loading=\"lazy\"\/><figcaption id=\"caption-attachment-141338\" class=\"wp-caption-text\">Lack of vitamin D led to lower autoimmune regulators in the thymus. (Artusa et al., <em>Science Advances<\/em>, 2024)<\/figcaption><\/figure>\n<p>The mice unable to produce vitamin D ended up with a thymus that was smaller and contained fewer cells. There were also biological signs of premature aging in the organ, and lower levels of a key autoimmune regulator.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>It shows how vitamin D deficiency can result in less protection against <a href=\"https:\/\/www.sciencealert.com\/nightmares-may-have-an-eerie-link-to-autoimmune-disease\">autoimmune diseases<\/a> \u2013 where the body mistakenly attacks its own cells, leading to health complications.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;An aging thymus leads to a leaky immune system,&#8221; <a href=\"https:\/\/www.mcgill.ca\/newsroom\/channels\/news\/how-vitamin-d-deficiency-can-lead-autoimmune-diseases-360580\">says<\/a> White. &#8220;This means the thymus becomes less effective at filtering out immune cells that could mistakenly attack healthy tissues, increasing the risk of autoimmune diseases like type 1  <a href=\"https:\/\/www.sciencealert.com\/diabetes\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73018\" data-postid=\"141335\" rel=\"nofollow noopener\" target=\"_self\">diabetes<\/a>.&#8221;<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Based on <a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(01)06580-1\/abstract\">earlier research<\/a>, experts think vitamin D is especially crucial in kids, as the all-important T cell training in the thymus happens up until <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1046\/j.1440-1711.2003.01191.x\">the age of 20<\/a>. As we get older, the benefits of vitamin D \u2013 at least in this regard \u2013 <a href=\"https:\/\/academic.oup.com\/edrv\/article\/40\/4\/1109\/5126915\">seem less clear-cut<\/a>.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>That makes these findings particularly relevant to youngsters. This has only been shown in mice so far, but our thymus functions in a similar way, so there are good reasons to believe the same biological processes are at play in humans.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>The researchers already have plans to investigate how vitamin D affects the human thymus (something that has not been studied before).<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>There&#8217;s still some debate <a href=\"https:\/\/www.sciencealert.com\/vitamin-d-tablets-may-be-worse-for-you-then-nothing-at-all\">about the effectiveness<\/a> of vitamin D supplements, though the general consensus is they can be beneficial <em>if<\/em> an individual is deficient \u2013 <a href=\"https:\/\/www.sciencealert.com\/common-vitamin-may-help-prevent-heart-attacks-new-evidence\">in certain areas of health<\/a>.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Now we know that missing out on this crucial vitamin, perhaps through a lack of daily sunlight, really can put our immune system at a disadvantage from our earliest years.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;If you have a young child, it&#8217;s important to consult with your healthcare provider to ensure they&#8217;re getting enough,&#8221; <a href=\"https:\/\/www.mcgill.ca\/newsroom\/channels\/news\/how-vitamin-d-deficiency-can-lead-autoimmune-diseases-360580\">says<\/a> White.<\/p>\n<p>The research has been published in <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adm9582\"><em>Science Advances<\/em><\/a>.<\/p>\n<\/p><\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.sciencealert.com\/vitamin-d-deficiency-can-trigger-autoimmune-conditions-heres-why\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vitamin D is important to our overall health, and now scientists have made some notable discoveries about how deficiency early in life can trigger problems with the body&#8217;s immune system. &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=121672\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-121672","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/121672","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=121672"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/121672\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=121672"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=121672"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=121672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}