{"id":124512,"date":"2024-11-11T07:19:35","date_gmt":"2024-11-11T00:19:35","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=124512"},"modified":"2024-11-11T07:19:35","modified_gmt":"2024-11-11T00:19:35","slug":"old-drug-now-called-a-magic-pill-regrows-hair-boosts-heart-health","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=124512","title":{"rendered":"Old drug now called a &#8220;magic pill&#8221; regrows hair, boosts heart health"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>A prescription medication that has been available in the U.S. since 1992, which many people recognize for treating hair loss and enlarged prostate, might have another significant benefit.<\/p>\n<p>Recent research suggests that a drug called finasteride could lower cholesterol levels and reduce the risk of heart disease. That\u2019s a surprising twist for a drug that\u2019s been around for decades.<\/p>\n<p>Curiosity led <a href=\"https:\/\/fshn.illinois.edu\/directory\/jaume6\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Jaume Amengual<\/a>, an assistant professor in the Department of Food Science and Human Nutrition at the <a href=\"https:\/\/fshn.illinois.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">University of Illinois<\/a>, to explore this unexpected connection. <\/p>\n<p>After noticing something unusual in a national survey, he decided to dig deeper. <\/p>\n<p>\u201cWhen we looked at the men taking finasteride in the survey, their <a href=\"https:\/\/www.earth.com\/news\/the-power-of-fish-oil-in-combating-high-cholesterol\/\" target=\"_blank\" rel=\"noreferrer noopener\">cholesterol levels<\/a> averaged 30 points lower than men not taking the drug. I thought we\u2019d see the opposite pattern, so it was very interesting,\u201d Dr. Amengual enthused.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-lowering-cholesterol-with-finasteride\">Lowering cholesterol with finasteride?<\/h2>\n<p>The initial clue came from the <a href=\"https:\/\/www.cdc.gov\/nchs\/nhanes\/index.htm\" target=\"_blank\" rel=\"noreferrer noopener\">National Health and Nutrition Examination Survey<\/a> conducted between 2009 and 2016. <\/p>\n<p>This survey collects health information from thousands of Americans. In this data, men using finasteride as a <a href=\"https:\/\/www.earth.com\/news\/new-natural-cure-male-baldness-highly-effective-sugar-2-deoxy-d-ribose\/\" target=\"_blank\" rel=\"noreferrer noopener\">hair loss treatment<\/a> had significantly lower cholesterol levels compared to those who weren\u2019t on the medication. <\/p>\n<p>A 30-point difference is substantial and caught the researchers\u2019 attention. But observational studies have limitations. The sample size of men over 50 using finasteride was small. <\/p>\n<p>\u201cThis was not a clinical study in which you can control everything perfectly,\u201d Amengual noted. \u201cIt was more of an observation that led us to say, \u2018Okay, now we\u2019ve seen this in people. Let\u2019s see what happens in mice.&#8217;\u201d<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-from-observation-to-experimentation\">From observation to experimentation<\/h2>\n<p>To get a clearer picture, the team turned to laboratory mice. Doctoral student <a href=\"https:\/\/www.linkedin.com\/in\/donald-molina-ba3099197\/?locale=es_ES\" target=\"_blank\" rel=\"noreferrer noopener\">Donald Molina Chaves<\/a> conducted experiments on mice predisposed to <a href=\"https:\/\/www.earth.com\/news\/fathers-diets-impact-the-heart-health-of-their-daughters\/\" target=\"_blank\" rel=\"noreferrer noopener\">atherosclerosis<\/a> \u2014 a condition where arteries narrow due to plaque buildup. <\/p>\n<p>The mice were fed different doses of finasteride along with a high-fat, high-cholesterol diet.<\/p>\n<p>\u201cMice that were given a high dose of finasteride showed lower <a href=\"https:\/\/www.earth.com\/news\/certain-gut-bacteria-lower-cholesterol-and-the-risk-of-heart-disease\/\" target=\"_blank\" rel=\"noreferrer noopener\">cholesterol levels<\/a> within the plasma as well as in the arteries,\u201d Molina Chaves said. \u201cThere were also fewer lipids and inflammatory markers in the liver.\u201d <\/p>\n<p>These findings suggested that finasteride doesn\u2019t just lower cholesterol in the blood but might also <a href=\"https:\/\/www.earth.com\/news\/lifestyle-choices-in-young-adulthood-impact-cognitive-ability-in-midlife\/\" target=\"_blank\" rel=\"noreferrer noopener\">reduce inflammation<\/a> and plaque formation in arteries.<\/p>\n<p>While the highest dose had significant effects, it\u2019s not a dose humans would take. <\/p>\n<p>\u201cIt\u2019s an incredibly high level of the drug. But we use mice as a model, and they are extremely resistant to things that would kill any of us,\u201d Amengual explained. \u201cSo it is not that wild when you think about it that way.\u201d <\/p>\n<p>The results in mice provide a direction for future human studies.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-finasteride-testosterone-and-heart-disease\">Finasteride, testosterone, and heart disease<\/h2>\n<p>So why would a hair loss drug affect <a href=\"https:\/\/www.earth.com\/news\/new-study-eating-eggs-is-not-bad-for-your-health-despite-years-of-warnings\/\" target=\"_blank\" rel=\"noreferrer noopener\">cholesterol levels<\/a>? It comes down to hormones. <\/p>\n<p>Finasteride works by blocking a protein that activates testosterone, specifically reducing levels of <a href=\"https:\/\/www.earth.com\/news\/men-with-low-testosterone-have-a-higher-risk-of-mortality\/\" target=\"_blank\" rel=\"noreferrer noopener\">dihydrotestosterone (DHT)<\/a>. DHT is linked to hair loss, prostate enlargement, and, as it turns out, possibly heart disease.<\/p>\n<p>\u201cI was reading about this medication one day, and I started to notice that there were not many long-term studies of the implications of the drug,\u201d Amengual said. <\/p>\n<p>\u201cInitially, it was just my own curiosity, based on the fact that hormone levels are known to have an effect on atherosclerosis, hair loss, and prostate issues. So, we decided to dig into it.\u201d<\/p>\n<p>Testosterone and its derivatives can influence the development of atherosclerosis. By altering these hormone levels, finasteride might indirectly impact cholesterol metabolism and inflammation, leading to improved <a href=\"https:\/\/www.earth.com\/news\/social-expectations-of-men-are-bad-for-their-heart-health\/\" target=\"_blank\" rel=\"noreferrer noopener\">heart health<\/a>.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-more-surprises-from-finasteride\">More surprises from finasteride<\/h2>\n<p>Interestingly, these findings might benefit more than just men dealing with hair loss or prostate issues. <\/p>\n<p>Transgender individuals undergoing hormone therapy often face a higher risk of heart disease due to hormonal changes. <\/p>\n<p>Finasteride is sometimes prescribed during gender transitions to manage hair loss triggered by hormone treatments.<\/p>\n<p>\u201cOver the past decade, doctors have started prescribing this drug for individuals transitioning either from male to female or female to male. In both cases, the hormonal changes can trigger hair loss,\u201d Amengual said. <\/p>\n<p>\u201cThe interesting thing is that transgender people are also at a higher risk of <a href=\"https:\/\/www.earth.com\/news\/depression-and-cardiovascular-diseases-are-genetically-linked\/\" target=\"_blank\" rel=\"noreferrer noopener\">cardiovascular diseases<\/a>. So this drug could have a potential beneficial effect to prevent cardiovascular disease not only in cis men, but also in transgender individuals.\u201d<\/p>\n<p>This opens up the possibility that finasteride could serve a dual purpose for transgender patients, helping with hair loss while also reducing heart disease risk.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-what-s-the-catch-understanding-finasteride-risks\">What\u2019s the catch? Understanding finasteride risks<\/h2>\n<p>Of course, no medication is without risks. Finasteride can cause side effects, and it\u2019s important to consider them. <\/p>\n<p>Some users experience <a href=\"https:\/\/www.earth.com\/news\/men-exhibit-better-sexual-health-eating-a-plant-based-vegan-diet\/\" target=\"_blank\" rel=\"noreferrer noopener\">sexual side effects<\/a> like decreased libido, erectile dysfunction, and reduced ejaculate volume. These effects happen because finasteride reduces DHT, which plays a role in sexual function.<\/p>\n<p>There have also been reports of psychological effects such as depression, anxiety, and mood changes. While not everyone experiences these, they\u2019re important to monitor. <\/p>\n<p>Physical side effects can include breast tenderness or enlargement, rashes, and swelling in the hands or feet. Rarely, finasteride can affect liver enzymes, so regular medical check-ups are recommended.<\/p>\n<p>A small percentage of users report persistent side effects even after stopping the medication, a condition referred to as Post-Finasteride Syndrome (PFS). <\/p>\n<p>Symptoms can include ongoing sexual dysfunction and psychological issues. Research is ongoing to understand and address these concerns.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-what-the-future-holds-for-finasteride\">What the future holds for finasteride<\/h2>\n<p>These discoveries suggest that finasteride could have a role in heart health beyond its current uses. More research is needed, though. <\/p>\n<p>Clinical trials involving people would help determine if the cholesterol-lowering effects seen in mice also occur in humans at practical doses.<\/p>\n<p>\u201cThis was not a clinical study in which you can control everything perfectly,\u201d Amengual emphasized. \u201cIt was more of an observation that led us to say, \u2018Okay, now we\u2019ve seen this in people. Let\u2019s see what happens in mice.&#8217;\u201d<\/p>\n<p>If future studies confirm these benefits, finasteride could become part of a strategy to prevent <a href=\"https:\/\/www.earth.com\/news\/artificial-sweetener-erythritol-sugar-substitute-linked-to-blood-clots-heart-disease\/\" target=\"_blank\" rel=\"noreferrer noopener\">heart disease<\/a>, especially in populations at higher risk.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-a-new-hope-proceed-with-eyes-wide-open\">A new hope? Proceed with eyes wide open<\/h2>\n<p>Finasteride has been around for a while, helping many with hair loss and prostate issues. Now, it might have a new role to play in promoting heart health. <\/p>\n<p>This could be significant not just for men but also for the transgender community and others at risk of cardiovascular disease.<\/p>\n<p>As with any medical treatment, it\u2019s crucial to consult healthcare providers before making changes. Finasteride\u2019s potential benefits must be balanced with its risks. But this research opens up exciting possibilities.<\/p>\n<p>The full study was published in the\u00a0<em><a href=\"https:\/\/www.jlr.org\/article\/S0022-2275(24)00012-9\/fulltext\" target=\"_blank\" rel=\"noreferrer noopener\">Journal of Lipid Research<\/a><\/em>.<\/p>\n<p>\u2014\u2013<\/p>\n<p>Like what you read? <a href=\"https:\/\/www.earth.com\/subscribe\/\" target=\"_blank\" rel=\"noreferrer noopener\">Subscribe to our newsletter<\/a> for engaging articles, exclusive content, and the latest updates.<\/p>\n<p>Check us out on <a href=\"https:\/\/www.earth.com\/earthsnap\/\" target=\"_blank\" rel=\"noreferrer noopener\">EarthSnap<\/a>, a free app brought to you by <a href=\"https:\/\/www.earth.com\/author\/eralls\/\" target=\"_blank\" rel=\"noreferrer noopener\">Eric Ralls<\/a> and Earth.com.<\/p>\n<p>\u2014\u2013<\/p>\n<\/div>\n<p><script>self.__next_f.push([1,\"d:[\\\"$\\\",\\\"html\\\",null,{\\\"lang\\\":\\\"en\\\",\\\"children\\\":[[\\\"$\\\",\\\"head\\\",null,{}],[\\\"$\\\",\\\"body\\\",null,{\\\"className\\\":\\\"__variable_55b985 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