{"id":125423,"date":"2024-11-13T17:21:01","date_gmt":"2024-11-13T10:21:01","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=125423"},"modified":"2024-11-13T17:21:01","modified_gmt":"2024-11-13T10:21:01","slug":"signs-of-lung-cancer-can-now-be-detected-when-you-exhale-sciencealert","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=125423","title":{"rendered":"Signs of Lung Cancer Can Now Be Detected When You Exhale : ScienceAlert"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>Ultra-sensitive monitors may one day routinely have the ability to detect <a href=\"https:\/\/en.wikipedia.org\/wiki\/Lung_cancer\">lung cancer<\/a> on someone&#8217;s breath.<\/p>\n<p>A small-scale test using a prototype device has demonstrated it can accurately detect the difference between eight healthy individuals and five people with lung  <a href=\"https:\/\/www.sciencealert.com\/cancer\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73077\" data-postid=\"143228\" rel=\"nofollow noopener\" target=\"_self\">cancer<\/a>.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>The device, built by a team led by researchers from Zhejiang University in China, looks for the compound <a href=\"https:\/\/en.wikipedia.org\/wiki\/Isoprene\">isoprene<\/a>. Lower isoprene levels have been identified as a potential <a href=\"https:\/\/www.worldscientific.com\/doi\/10.1142\/S1793545822500298\">indicator of lung cancer<\/a>, but it&#8217;s a small shift that&#8217;s very difficult to measure.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Now, we have the technology to do it \u2013 at least in a proof-of-concept form. As with most cancers, the earlier lung cancer is detected the better the chances of effectively treating it \u2013 and there&#8217;s potential here for a simple, affordable, quick, and non-invasive way of checking for the disease.<\/p>\n<figure id=\"attachment_143231\" aria-describedby=\"caption-attachment-143231\" style=\"width: 642px\" class=\"wp-caption alignnone\"><img decoding=\"async\" src=\"https:\/\/www.sciencealert.com\/images\/2024\/11\/SensingDevice.jpg\" alt=\"Sensing device\" width=\"642\" height=\"590\" class=\"wp-image-143231 size-full\" srcset=\"https:\/\/www.sciencealert.com\/images\/2024\/11\/SensingDevice.jpg 642w, https:\/\/www.sciencealert.com\/images\/2024\/11\/SensingDevice-452x415.jpg 452w, https:\/\/www.sciencealert.com\/images\/2024\/11\/SensingDevice-600x551.jpg 600w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" loading=\"lazy\"\/><figcaption id=\"caption-attachment-143231\" class=\"wp-caption-text\">Diagram summarizing the research. (Cheng et al., <em>ACS Sensors<\/em>, 2024)<\/figcaption><\/figure>\n<p>&#8220;Our work not only provides a breakthrough in low-cost, non-invasive cancer screening through breath analysis but also advances the rational design of cutting-edge gas sensing materials,&#8221; <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acssensors.4c01298\">write<\/a> the researchers in their published paper.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>To achieve the required sensitivity in their breath monitor, the researchers <a href=\"https:\/\/www.acs.org\/pressroom\/presspacs\/2024\/november\/detecting-evidence-of-lung-cancer-in-exhaled-breath.html\">used nanoflakes<\/a> made from a combination of platinum, indium, nickel, and oxygen. As the isoprene hits the nanoflakes, electron release is sparked in a way that can be measured.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>The end result was a sensor that could detect isoprene levels as low as 2 ppb (parts per billion) \u2013 a notable improvement on <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acssensors.7b00976\">existing technology<\/a>. Of the 13 people tested, the five with cancer had isoprene levels lower than 40 ppb on their breath, whereas in the healthy group of eight people the level was over 60 ppb.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Impressively, in lab tests the nanoflakes were shown to be able to identify isoprene specifically among other chemicals. They can also operate in conditions with higher humidity, which is essential for a breath monitor. However, even the researchers admit there&#8217;s still a long way to go.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;Targeting the substantial market of lung cancer diagnosis, future commercialization of the technology requires continuous research on the sensing materials, the accurate relationship between breath isoprene and lung cancer, data analysis algorithms, and integration techniques with portable devices,&#8221; <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acssensors.4c01298\">write<\/a> the researchers.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>The damage done by lung cancer affects some of the body&#8217;s key metabolic processes, and it&#8217;s thought that those changes are somehow <a href=\"https:\/\/www.jstage.jst.go.jp\/article\/biomedres\/40\/1\/40_29\/_article\">affecting isoprene<\/a> in a way that can reveal the presence of the disease.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Lung cancer is <a href=\"https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/lung-cancer\">the leading cause<\/a> of cancer-related deaths worldwide \u2013 mostly due to smoking \u2013 and was responsible for some 1.8 million fatalities in 2020. It&#8217;s also one of the cancers that is often detected at a late stage, <a href=\"https:\/\/www.sciencealert.com\/this-pill-can-halve-the-risk-of-death-after-lung-cancer-scientists-say\">when treatments<\/a> are less effective, making studies of this type particularly urgent.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;Continuous research on the relationship between breath isoprene levels and lung cancer, as well as on the various influencing factors (e.g., age, health status), can help refine and further commercialize the technology,&#8221; <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acssensors.4c01298\">write<\/a> the researchers.<\/p>\n<p>The research has been published in <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acssensors.4c01298\"><em>ACS Sensors<\/em><\/a>.<\/p>\n<\/p><\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.sciencealert.com\/signs-of-lung-cancer-can-now-be-detected-when-you-exhale\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ultra-sensitive monitors may one day routinely have the ability to detect lung cancer on someone&#8217;s breath. A small-scale test using a prototype device has demonstrated it can accurately detect the &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=125423\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-125423","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/125423","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=125423"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/125423\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=125423"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=125423"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=125423"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}