{"id":127428,"date":"2024-11-18T23:28:40","date_gmt":"2024-11-18T16:28:40","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=127428"},"modified":"2024-11-18T23:28:40","modified_gmt":"2024-11-18T16:28:40","slug":"cannabis-use-during-pregnancy-rewires-the-fetal-brain","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=127428","title":{"rendered":"Cannabis use during pregnancy rewires the fetal brain"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>THC, the main psychoactive ingredient in cannabis, is being used by more pregnant women as the legalization of recreational cannabis gains ground. <\/p>\n<p>Women who are expecting often use cannabis for morning sickness, lower back pain, or anxiety relief.<\/p>\n<p>Recent figures indicate that up to 1 in 5 pregnant women in the U.S. now use cannabis. However, growing research suggests that THC exposure could pose significant risks to the developing fetus.<\/p>\n<p>A recent study highlights how prenatal exposure to THC may increase the risk of opioid addiction later in life.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-thc-rewires-the-fetal-brain\">THC rewires the fetal brain<\/h2>\n<p>The preclinical animal study, led by researchers at the <a href=\"https:\/\/www.medschool.umaryland.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">University of Maryland School of Medicine<\/a> and published in the journal <em>Science Advances<\/em>, revealed that prenatal exposure to THC rewires the fetal brain.<\/p>\n<p>According to the study, THC made certain <a href=\"https:\/\/www.earth.com\/news\/covid-19-makes-you-feel-moody-and-sad-by-depleting-dopamine\/\" target=\"_blank\" rel=\"noreferrer noopener\">dopamine<\/a> neurons hyperactive, resulting in a marked increase in dopamine release and an amplified response to reward-related cues, such as a signal indicating the availability of food or an opioid drug.<\/p>\n<p>\u201cDoctors are contending with an explosion of cannabis use, and the THC content has quadrupled from what it was a generation ago,\u201d said Dr. Joseph Cheer, a professor of Neurobiology and Psychiatry at the University of Maryland School of Medicine.<\/p>\n<p>\u201cIt demonstrates the enduring consequences that prenatal cannabis exposure exerts on the brain\u2019s reward system, which ultimately results in a neurobiological vulnerability to <a href=\"https:\/\/www.earth.com\/news\/opioid-related-deaths-are-on-the-rise-among-young-people\/\" target=\"_blank\" rel=\"noreferrer noopener\">opioid<\/a> drugs.\u201d<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-prenatal-exposure-to-thc\">Prenatal exposure to THC<\/h2>\n<p>The study revealed that prenatal exposure to THC led to significant changes in the brain\u2019s reward system, particularly in male animals. <\/p>\n<p>These animals displayed an exaggerated surge in the \u201creward-seeking\u201d brain chemical dopamine when exposed to opioid drugs during adolescence, compared to those not exposed to THC.<\/p>\n<p>Even moderate doses of THC \u2014 equivalent to one to two joints per day in humans \u2014 altered how the fetal brain processed rewards, fostering behavior suggestive of increased opioid-seeking.<\/p>\n<p>This behavior was confirmed by follow-up experiments where tiny sensors implanted in their brains detected heightened dopamine release and over-activation of neurons linked to reward-seeking behavior.<\/p>\n<p>\u201cThese observations support the hypothesis of a hypersensitized \u2018wanting\u2019 system that develops in the brain after exposure to THC during <a href=\"https:\/\/www.earth.com\/news\/prenatal-cannabis-exposure-has-unexpected-effect-on-infant-language\/\" target=\"_blank\" rel=\"noreferrer noopener\">prenatal<\/a> development,\u201c said Dr. Cheer. <\/p>\n<p>\u201cInterestingly, we found that this opioid-seeking phenotype occurs significantly more in males compared to females, and we are currently performing research with our colleagues at UMSOM to determine why this is the case.\u201d<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-cannabis-health-benefits-outside-of-pregnancy\">Cannabis health benefits outside of pregnancy<\/h2>\n<p>For those who are not pregnant, and don\u2019t expect to become pregnant soon, cannabis has been shown to provide mental and physical <a href=\"https:\/\/www.earth.com\/news\/cannabis-smokers-not-lazy-unmotivated-despite-stereotypes\/\" target=\"_blank\" rel=\"noreferrer noopener\">health benefits<\/a>.<\/p>\n<p>Many people have found that cannabis can help relieve chronic pain. By interacting with the body\u2019s endocannabinoid system, compounds like THC and CBD in cannabis may <a href=\"https:\/\/www.earth.com\/news\/patients-with-chronic-pain-are-turning-to-cannabis-for-relief\/\" target=\"_blank\" rel=\"noreferrer noopener\">reduce discomfort<\/a> from conditions like arthritis, migraines, and neuropathic pain. <\/p>\n<p>This interaction can lead to improved daily functioning and a better quality of life for those who struggle with persistent pain.<\/p>\n<p>Cannabis is also known for easing nausea and boosting appetite, which is particularly<a href=\"https:\/\/www.earth.com\/news\/cannabis-may-be-a-highly-effective-treatment-for-cancer-patients\/\" target=\"_blank\" rel=\"noreferrer noopener\"> beneficial for cancer patients<\/a> undergoing chemotherapy, or people dealing with conditions like HIV\/AIDS. <\/p>\n<p>Some users report that it helps <a href=\"https:\/\/www.earth.com\/news\/chemical-found-in-cannabis-plants-can-actually-reduce-cannabis-induced-anxiety\/\" target=\"_blank\" rel=\"noreferrer noopener\">reduce anxiety<\/a> and <a href=\"https:\/\/www.earth.com\/news\/natures-sleep-aid-cannabinol-shows-promise-as-a-safe-sedative\/\" target=\"_blank\" rel=\"noreferrer noopener\">improve sleep<\/a>, making it a potential aid for insomnia or stress-related issues.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-what-happens-next\">What happens next?<\/h2>\n<p>Dr. Cheer and his colleague, Dr. Mary Kay Lobo, co-direct the Center for Substance Use in Pregnancy at the University of Maryland School of Medicine\u2019s Kahlert Institute for Addiction Medicine. <\/p>\n<p>Their ongoing research aims to further understand the long-term impact of <a href=\"https:\/\/www.earth.com\/news\/prenatal-thc-exposure-linked-to-life-long-health-risks\/\" target=\"_blank\" rel=\"noreferrer noopener\">drug exposure during pregnancy<\/a>.<\/p>\n<p>\u201cWe need to more fully understand the enduring effects of THC exposure in the womb and whether we can reverse some of the deleterious effects through CRISPR-based gene therapies or repurposed drugs,\u201d said study co-author Dr. Dean Mark T. Gladwin.<\/p>\n<p>\u201cWe also need to provide better advice to pregnant patients, many of whom are using cannabis to help control anxiety because they think this drug is safer for their baby than traditional anti-anxiety medications.\u201d<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-cannabis-pregnancy-and-health\">Cannabis, pregnancy, and health<\/h2>\n<p>The findings suggest that there is a need for more exhaustive public health programs to educate pregnant women on the long-term effects that coincide with <a href=\"https:\/\/www.earth.com\/news\/record-number-of-americans-are-high-on-marijuana-at-work\/\" target=\"_blank\" rel=\"noreferrer noopener\">marijuana<\/a> exposure during pregnancy. <\/p>\n<p>Previous studies on cannabis use during pregnancy have also raised significant concerns about its potential impacts on fetal development and maternal health.<\/p>\n<p>For example, studies have linked prenatal cannabis exposure to deficits in attention, memory, and executive functioning in children. <\/p>\n<p>Furthermore, cannabis use during pregnancy is associated with an increased risk of low birth weight, which can lead to complications such as developmental delays and long-term health issues.<\/p>\n<p>Guidelines on pregnancy and provision of adequate resources for pregnant women could be created and harmonized in collaboration between healthcare providers, researchers, and policymakers.<\/p>\n<p>Investments in supplemental research, which would include human studies, may also clarify how exposures to THC impact the fetal brain in its developing state. <\/p>\n<p>The study is published in the journal <em><a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adq5652\" target=\"_blank\" rel=\"noreferrer noopener\">Science Advances<\/a><\/em>.<\/p>\n<p>\u2014\u2013<\/p>\n<p>Like what you read? <a href=\"https:\/\/www.earth.com\/subscribe\/\" target=\"_blank\" rel=\"noreferrer noopener\">Subscribe to our newsletter<\/a> for engaging articles, exclusive 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