{"id":128362,"date":"2024-11-21T09:33:50","date_gmt":"2024-11-21T02:33:50","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=128362"},"modified":"2024-11-21T09:33:50","modified_gmt":"2024-11-21T02:33:50","slug":"fasting-style-diet-seems-to-result-in-dynamic-changes-in-human-brain-sciencealert","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=128362","title":{"rendered":"Fasting-Style Diet Seems to Result in Dynamic Changes in Human Brain : ScienceAlert"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>Scientists looking to tackle our ongoing <a href=\"https:\/\/www.sciencealert.com\/there-isn-t-just-one-obesity-gene-linked-to-being-overweight\">obesity crisis<\/a> have made an important discovery: Intermittent calorie restriction leads to significant changes both in the gut and the brain, which may open up new options for maintaining a healthy weight.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Researchers from China studied 25 volunteers classed as obese over a period of 62 days, during which they took part in an intermittent energy restriction (IER) program \u2013 a regime that involves careful control of calorie intake and relative <a href=\"https:\/\/www.sciencealert.com\/is-intermittent-fasting-or-calorie-counting-better-for-weight-loss-new-study-weighs-in\">fasting on some days<\/a>.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Not only did the participants in the study lose weight \u2013 7.6 kilograms (16.8 pounds) or 7.8 percent of their body weight on average \u2013 there was also evidence of shifts in the activity of obesity-related regions of the brain, and in the make-up of <a href=\"https:\/\/www.sciencealert.com\/we-contain-a-variety-of-microbiomes-heres-a-look-at-a-few-of-the-most-important\">gut bacteria<\/a>.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;Here we show that an IER diet changes the human brain-gut-microbiome axis,&#8221; <a href=\"https:\/\/www.frontiersin.org\/news\/2023\/12\/20\/frontiers-cellular-infection-microbiology-weight-loss-changes-microbiome-brain-coupled\">said<\/a> health researcher Qiang Zeng from the Second Medical Center and National Clinical Research Center for Geriatric Diseases in China when the results were published in December 2023.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;The observed changes in the gut microbiome and in the activity in addiction-related brain regions during and after weight loss are highly dynamic and coupled over time.&#8221;<\/p>\n<figure id=\"attachment_144243\" aria-describedby=\"caption-attachment-144243\" style=\"width: 642px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.sciencealert.com\/images\/2024\/11\/IntermittentFastingConceptFoodOnPlate642.jpg\" alt=\"Food on a wooden plate in one section with cutlery placed to like hands on a clock\" width=\"642\" height=\"500\" class=\"size-full wp-image-144243\" srcset=\"https:\/\/www.sciencealert.com\/images\/2024\/11\/IntermittentFastingConceptFoodOnPlate642.jpg 642w, https:\/\/www.sciencealert.com\/images\/2024\/11\/IntermittentFastingConceptFoodOnPlate642-533x415.jpg 533w, https:\/\/www.sciencealert.com\/images\/2024\/11\/IntermittentFastingConceptFoodOnPlate642-600x467.jpg 600w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" loading=\"lazy\"\/><figcaption id=\"caption-attachment-144243\" class=\"wp-caption-text\">An IER diet involves careful control of calorie intake and relative fasting on some days. (<a href=\"https:\/\/www.canva.com\/photos\/MAFjkkQB-bU\/\">vetrestudio\/Canva<\/a>)<\/figcaption><\/figure>\n<p>It&#8217;s not clear what causes these changes, or whether the gut is influencing the brain or vice versa. However, we do know that the gut and the brain are <a href=\"https:\/\/www.sciencealert.com\/massive-study-pinpoints-specific-gut-bacteria-linked-to-alzheimers\">closely linked<\/a>, so treating certain regions of the brain could be a way to control food intake.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>The changes in brain activity, spotted via <a href=\"https:\/\/en.wikipedia.org\/wiki\/Functional_magnetic_resonance_imaging\">functional magnetic resonance imaging<\/a> (fMRI) scans, were in regions known to be important in the regulation of appetite and addiction \u2013 including the <a href=\"https:\/\/en.wikipedia.org\/wiki\/Orbital_part_of_inferior_frontal_gyrus\">inferior frontal orbital gyrus<\/a>.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>What&#8217;s more, the gut microbiome changes, analyzed via stool samples and blood measurements, were linked to particular brain regions.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>For example, the bacteria <a href=\"https:\/\/en.wikipedia.org\/wiki\/Coprococcus\"><em>Coprococcus comes<\/em><\/a> and <a href=\"https:\/\/en.wikipedia.org\/wiki\/Anaerobutyricum_hallii\"><em>Eubacterium hallii<\/em><\/a> were negatively associated with activity in the left inferior frontal orbital gyrus, an area involved in executive function, including our willpower when it comes to food intake.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;The gut microbiome is thought to communicate with the brain in a complex, two-directional way,&#8221; <a href=\"https:\/\/www.frontiersin.org\/news\/2023\/12\/20\/frontiers-cellular-infection-microbiology-weight-loss-changes-microbiome-brain-coupled\">said<\/a> medical scientist Xiaoning Wang from the State Clinic Center for Geriatrics in China.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;The microbiome produces neurotransmitters and neurotoxins which access the brain through nerves and the blood circulation. In return the brain controls eating behavior, while nutrients from our diet change the composition of the gut microbiome.&#8221;<\/p>\n<figure id=\"attachment_144241\" aria-describedby=\"caption-attachment-144241\" style=\"width: 642px\" class=\"wp-caption aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.sciencealert.com\/images\/2024\/11\/ChildEatingWatermelon642-1.jpg\" alt=\"A child eating a slice of watermelon\" width=\"642\" height=\"500\" class=\"size-full wp-image-144241\" srcset=\"https:\/\/www.sciencealert.com\/images\/2024\/11\/ChildEatingWatermelon642-1.jpg 642w, https:\/\/www.sciencealert.com\/images\/2024\/11\/ChildEatingWatermelon642-1-533x415.jpg 533w, https:\/\/www.sciencealert.com\/images\/2024\/11\/ChildEatingWatermelon642-1-600x467.jpg 600w\" sizes=\"auto, (max-width: 642px) 100vw, 642px\" loading=\"lazy\"\/><figcaption id=\"caption-attachment-144241\" class=\"wp-caption-text\">Nutrients from our diet change the composition of the gut microbiome. (<a href=\"https:\/\/www.canva.com\/photos\/MAFHfMD27oY\/\">corelens\/Canva<\/a>)<\/figcaption><\/figure>\n<p><a href=\"https:\/\/www.who.int\/news\/item\/04-03-2022-world-obesity-day-2022-accelerating-action-to-stop-obesity\">More than a billion<\/a> people worldwide are estimated to have obesity, which leads to an increased risk for a multitude of different health issues, from  <a href=\"https:\/\/www.sciencealert.com\/cancer\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73077\" data-postid=\"144239\" rel=\"nofollow noopener\" target=\"_self\">cancer<\/a> to heart disease.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>Knowing more about how our brains and guts are <a href=\"https:\/\/www.sciencealert.com\/obesity-can-trigger-lasting-changes-in-the-brains-nutrient-response-study-finds\">dependent on each other<\/a> could make a huge difference in effectively preventing and reducing obesity.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;The next question to be answered is the precise mechanism by which the gut microbiome and the brain communicate in obese people, including during weight loss,&#8221; <a href=\"https:\/\/www.frontiersin.org\/news\/2023\/12\/20\/frontiers-cellular-infection-microbiology-weight-loss-changes-microbiome-brain-coupled\">said<\/a> biomedical scientist Liming Wang from the Chinese Academy of Sciences.<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>&#8220;What specific gut microbiome and brain regions are critical for successful weight loss and maintaining a healthy weight?&#8221;<\/p>\n<p><!-- START single\/mrec --><br \/>\n<!-- END single\/mrec --><\/p>\n<p>The research was published in <a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fcimb.2023.1269548\/full\"><em>Frontiers in Cellular and Infection Microbiology<\/em><\/a>.<\/p>\n<p><em>An earlier version of this article was published in December 2023.<\/em><\/p>\n<\/p><\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.sciencealert.com\/fasting-style-diet-seems-to-result-in-dynamic-changes-in-human-brain\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists looking to tackle our ongoing obesity crisis have made an important discovery: Intermittent calorie restriction leads to significant changes both in the gut and the brain, which may open &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=128362\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-128362","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/128362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=128362"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/128362\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=128362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=128362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=128362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}