{"id":133122,"date":"2024-12-04T06:48:11","date_gmt":"2024-12-03T23:48:11","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=133122"},"modified":"2024-12-04T06:48:11","modified_gmt":"2024-12-03T23:48:11","slug":"aging-is-it-a-disease-a-process-or-something-else","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=133122","title":{"rendered":"Aging: Is It a Disease, a Process, or Something Else?"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p><strong>Summary: <\/strong>A survey of experts in aging research reveals significant disagreements on fundamental questions, such as \u201cWhat is aging?\u201d and \u201cWhen does it begin?\u201d Responses ranged from seeing aging as a demographic increase in mortality to a lifelong process or even a developmental stage, with no consensus on whether aging is a disease.<\/p>\n<p>Despite these differences, scientists generally agree that aging is a process and is inherently harmful. The findings highlight the need for the field to reflect on its foundational definitions to advance aging research effectively.<\/p>\n<p><strong>Key Facts:<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>Experts disagree on whether aging begins at gametogenesis, adulthood, or earlier.<\/li>\n<li>There is no consensus on defining aging as a disease or a normal process.<\/li>\n<li>Scientists agree aging is a process and is inherently deleterious.<\/li>\n<\/ul>\n<p><strong>Source: <\/strong>Brigham and Women\u2019s Hospital<\/p>\n<p><strong>Vadim N. Gladyshev and 80 colleagues surveyed the participants of the 2022 Systems Aging Gordon Research Conference to explore how researchers of aging perceive their subject of study. <\/strong><\/p>\n<p>The\u00a0authors found wide disagreement on fundamental questions, including \u201cwhat is aging?\u201d and \u201cwhat causes aging?\u201d.<\/p>\n<p>The collected responses indicated that some of the 103 professors, postdocs, graduate students, industry professionals, and other experts in the survey saw aging as a demographic increase in mortality rate, while other respondents saw aging as a loss of function over time, while still other respondents saw aging as the accumulation of damage or an overall pathological decline.<\/p>\n<figure class=\"wp-block-image size-full\"><picture fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-106699\"><source type=\"image\/webp\" srcset=\"https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience.jpg.webp 1200w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-300x200.jpg.webp 300w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-770x513.jpg.webp 770w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-1155x770.jpg.webp 1155w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-370x247.jpg.webp 370w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-293x195.jpg.webp 293w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-150x100.jpg.webp 150w\" sizes=\"(max-width: 1200px) 100vw, 1200px\"\/><img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"800\" src=\"https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience.jpg\" alt=\"This shows people at various ages.\" srcset=\"https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience.jpg 1200w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-300x200.jpg 300w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-770x513.jpg 770w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-1155x770.jpg 1155w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-370x247.jpg 370w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-293x195.jpg 293w, https:\/\/neurosciencenews.com\/files\/2024\/12\/aging-science-neuroscience-150x100.jpg 150w\" sizes=\"(max-width: 1200px) 100vw, 1200px\"\/> <\/picture><figcaption class=\"wp-element-caption\">There was no consensus on whether aging is a disease or not and respondents did not even agree on the question of whether the field ought to have a single consensus definition of aging. Credit: Neuroscience News<\/figcaption><\/figure>\n<p>Some respondents saw aging as a normal developmental stage.<\/p>\n<p>In terms of when aging begins, some respondents saw aging as a lifelong process that begins as early as gametogenesis\u2014when the gametes that will form the individual are made\u2014while others saw aging as a process specific to adults.<\/p>\n<p>Some disagreements indicated a difference in perspective between those who see aging as something that happens to cells and those who see aging as a process that happens to organisms.<\/p>\n<p>There was no consensus on whether aging is a disease or not and respondents did not even agree on the question of whether the field ought to have a single consensus definition of aging.<\/p>\n<p>Yet behind the wide disagreement there were some implied points of agreement: aging exists; aging is a process; and aging is inherently deleterious.<\/p>\n<p>According to the authors, the\u00a0field could benefit from\u00a0considering its foundations to better move forward.<\/p>\n<h2 class=\"wp-block-heading\">About this aging research news<\/h2>\n<p class=\"has-background\" style=\"background-color:#ffffe8\"><strong>Author: <\/strong><a href=\"http:\/\/neurosciencenews.com\/cdn-cgi\/l\/email-protection#2056474c41445953484556604257480e484152564152440e454455\" target=\"_blank\" rel=\"noreferrer noopener\">Vadim N. Gladyshev<\/a><br \/><strong>Source: <\/strong><a href=\"https:\/\/bwh.harvard.edu\" target=\"_blank\" rel=\"noreferrer noopener\">Brigham and Women\u2019s Hospital<\/a><br \/><strong>Image: <\/strong>The image is credited to Neuroscience News<\/p>\n<p class=\"has-background\" style=\"background-color:#ffffe8\"><strong>Original Research: <\/strong>Open access.<br \/>\u201c<a href=\"https:\/\/doi.org\/10.1093\/pnasnexus\/pgae499\" target=\"_blank\" rel=\"noreferrer noopener\">Disagreement on foundational principles of biological aging<\/a>\u201d by Vadim N. Gladyshev et al. <em>PNAS Nexus<\/em><\/p>\n<hr class=\"wp-block-separator has-text-color has-pale-cyan-blue-color has-alpha-channel-opacity has-pale-cyan-blue-background-color has-background\"\/>\n<p><strong>Abstract<\/strong><\/p>\n<p><strong>Disagreement on foundational principles of biological aging<\/strong><\/p>\n<p>To gain insight into how researchers of aging perceive the process they study, we conducted a survey among experts in the field. While highlighting some common features of aging, the survey exposed broad disagreement on the foundational issues.<\/p>\n<p>What is aging? What causes it? When does it begin? What constitutes rejuvenation?<\/p>\n<p>Not only was there no consensus on these and other core questions, but none of the questions received a majority opinion\u2014even regarding the need for consensus itself.<\/p>\n<p>Despite many researchers believing they understand aging, their understanding diverges considerably. Importantly, as different processes are labeled as \u201caging\u201d by researchers, different experimental approaches are prioritized.<\/p>\n<p>The survey shed light on the need to better define which aging processes this field should target and what its goals are. It also allowed us to categorize contemporary views on aging and rejuvenation, revealing critical, yet largely unanswered, questions that appear disconnected from the current research focus.<\/p>\n<p>Finally, we discuss ways to address the disagreement, which we hope will ultimately aid progress in the field.<\/p>\n<p> <!-- Form created by Optin Forms plugin by WPKube: create beautiful optin forms with ease! --> <!-- https:\/\/wpkube.com\/ --><!--optinforms-form5-container--> <!-- \/ Optin Forms --> <\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/neurosciencenews.com\/aging-disease-process-28168\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summary: A survey of experts in aging research reveals significant disagreements on fundamental questions, such as \u201cWhat is aging?\u201d and \u201cWhen does it begin?\u201d Responses ranged from seeing aging as &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=133122\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-133122","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/133122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=133122"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/133122\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=133122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=133122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=133122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}