{"id":133602,"date":"2024-12-05T13:20:54","date_gmt":"2024-12-05T06:20:54","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=133602"},"modified":"2024-12-05T13:20:54","modified_gmt":"2024-12-05T06:20:54","slug":"sleep-apnea-may-increase-risk-of-wet-macular-degeneration","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=133602","title":{"rendered":"Sleep Apnea May Increase Risk of Wet Macular Degeneration"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p><strong>Summary: <\/strong>A new study has linked moderate-to-severe obstructive sleep apnea (OSA), characterized by low oxygen levels overnight, with an increased risk of developing wet age-related macular degeneration (AMD). The research suggests nocturnal hypoxia could affect the oxygen-sensitive retina, contributing to AMD progression.<\/p>\n<p>Conducted with 225 participants using home-based oximeters, the study found that treating OSA might reduce the risk of AMD. Researchers aim to validate these findings and explore whether managing sleep apnea can slow vision loss in at-risk individuals.<\/p>\n<p><strong>Key Facts:<\/strong><\/p>\n<ul class=\"wp-block-list\">\n<li>Moderate-to-severe OSA is linked to increased risk of wet AMD.<\/li>\n<li>Nocturnal hypoxia may harm the retina, which has high oxygen demands at night.<\/li>\n<li>Treating OSA could potentially reduce the risk of developing wet AMD.<\/li>\n<\/ul>\n<p><strong>Source: <\/strong>Centre for Eye Research Australia<\/p>\n<p><strong>A Center for Eye Research Australia study has linked low levels of oxygen in the blood overnight\u2014a common sign of obstructive sleep apnea\u2014with wet age-related macular degeneration.<\/strong><\/p>\n<p>The findings,\u00a0published\u00a0in\u00a0<em>Clinical and Experimental Ophthalmology<\/em>, suggest obstructive sleep apnea (OSA) could be a modifiable risk factor associated with the \u201cwet\u201d form of late-stage age-related macular degeneration (AMD).<\/p>\n<figure class=\"wp-block-image size-full\"><picture fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-106745\"><source type=\"image\/webp\" srcset=\"https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience.jpg.webp 1200w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-300x200.jpg.webp 300w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-770x513.jpg.webp 770w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-1155x770.jpg.webp 1155w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-370x247.jpg.webp 370w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-293x195.jpg.webp 293w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-150x100.jpg.webp 150w\" sizes=\"(max-width: 1200px) 100vw, 1200px\"\/><img fetchpriority=\"high\" decoding=\"async\" width=\"1200\" height=\"800\" src=\"https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience.jpg\" alt=\"This shows a man sleeping.\" srcset=\"https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience.jpg 1200w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-300x200.jpg 300w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-770x513.jpg 770w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-1155x770.jpg 1155w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-370x247.jpg 370w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-293x195.jpg 293w, https:\/\/neurosciencenews.com\/files\/2024\/12\/amd-sleep-apnea-neuroscience-150x100.jpg 150w\" sizes=\"(max-width: 1200px) 100vw, 1200px\"\/> <\/picture><figcaption class=\"wp-element-caption\">The results showed that moderate-to-severe OSA, which results in lower levels of oxygen in the blood overnight, was associated with an increased risk of having wet AMD compared to those without OSA. Credit: Neuroscience News<\/figcaption><\/figure>\n<p>University of Melbourne Master\u2019s student Attiqa Chaudhary along with members of the CERA\u2019s Macular Research unit, led by Professor Robyn Guymer AM, conducted the study. They also worked with sleep disorder expert Professor Matthew Naughton from Monash University to analyze the results.<\/p>\n<p>The team conducted a sleep study involving 225 participants aged over 50 with different stages of AMD and measured their oxygen levels over three nights with a home-based finger oximeter. Their level of OSA was calculated based on the oxygen levels in their blood overnight.<\/p>\n<p>The results showed that moderate-to-severe OSA, which results in lower levels of oxygen in the blood overnight, was associated with an increased risk of having wet AMD compared to those without OSA.<\/p>\n<p>Study co-supervisor Dr. Carla Abbott says the findings are something clinicians should be aware of.<\/p>\n<p>\u201cLike AMD, sleep apnea mainly affects people over the age of 50 and many people don\u2019t realize they have it,\u201d Dr. Abbott says.<\/p>\n<p>\u201cIf this association is validated it may well be worth asking people with high-risk early stages of AMD if they have any symptoms suggestive of OSA, as treating OSA might reduce the risk of developing wet AMD.\u201d<\/p>\n<h2 class=\"wp-block-heading\">Nocturnal hypoxia and wet AMD<\/h2>\n<p>Nocturnal hypoxia often occurs as a result of OSA, where a person\u2019s airway becomes blocked or narrowed overnight, reducing their oxygen intake.<\/p>\n<p>A lack of oxygen overnight can cause various health issues over time, but the light-sensitive retina in the eye may be particularly sensitive to small drops in oxygen levels.<\/p>\n<p>\u201cThe retina is very active at night\u2014it has its highest need for energy while it recovers from the day,\u201d says Dr. Abbott.<\/p>\n<p>Many people diagnosed with sleep apnea use a CPAP device at night, which helps them breathe easier by providing a constant flow of air through a mask.<\/p>\n<p>\u201cIf people aren\u2019t currently getting treatment, it\u2019s putting them at risk over years of not sleeping properly and having low oxygen at night, which could be a contributing factor to AMD, in particular wet AMD,\u201d says Dr. Abbott.<\/p>\n<p>Currently known risk factors for AMD include smoking status, diet, age and genetics.<\/p>\n<p>Dr. Abbott says the team will need to conduct larger studies to better understand this association and, if validated, will explore whether treating sleep apnea has a clinically meaningful impact on reducing progression to wet AMD.<\/p>\n<p>The work is part of the wider Synergy High Risk AMD Study, which is investigating AMD and the potential underlying causes that make some people more likely to lose their vision.<\/p>\n<h2 class=\"wp-block-heading\">About this visual neuroscience research news<\/h2>\n<p class=\"has-background\" style=\"background-color:#ffffe8\"><strong>Author:<\/strong><a href=\"https:\/\/www.cera.org.au\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong> <\/strong>Carla Abbott<\/a><br \/><strong>Source: <\/strong><a href=\"https:\/\/www.cera.org.au\/\" target=\"_blank\" rel=\"noreferrer noopener\">Centre for Eye Research Australia<\/a><br \/><strong>Contact: <\/strong>Carla Abbott \u2013 Centre for Eye Research Australia<br \/><strong>Image: <\/strong>The image is credited to Neuroscience News<\/p>\n<p class=\"has-background\" style=\"background-color:#ffffe8\"><strong>Original Research: <\/strong>Open access.<br \/>\u201c<a href=\"https:\/\/doi.org\/10.1111\/ceo.14428\" target=\"_blank\" rel=\"noreferrer noopener\">Nocturnal hypoxia and age\u2010related macular degeneration<\/a>\u201d by Attiqa Chaudhary et al. <em><em>Clinical and Experimental Ophthalmology<\/em><\/em><\/p>\n<hr class=\"wp-block-separator has-text-color has-pale-cyan-blue-color has-alpha-channel-opacity has-pale-cyan-blue-background-color has-background\"\/>\n<p><strong>Abstract<\/strong><\/p>\n<p><strong>Nocturnal hypoxia and age\u2010related macular degeneration<\/strong><\/p>\n<h3 class=\"wp-block-heading\" id=\"ceo14428-sec-0001-title\">Background<\/h3>\n<p>Nocturnal hypoxia is common, under-diagnosed and is found in the same demographic at risk of age-related macular degeneration (AMD). The objective of this study was to determine any association between nocturnal hypoxia and AMD, its severity, and the high-risk sub-phenotype of reticular pseudodrusen (RPD).<\/p>\n<h3 class=\"wp-block-heading\" id=\"ceo14428-sec-0002-title\">Methods<\/h3>\n<p>This cross-sectional study included participants aged \u226550\u2009years with AMD, or normal controls, exclusive of those on treatment for obstructive sleep apnoea. All participants had at home, overnight (up to 3 nights) pulse oximetry recordings and multimodal imaging to classify AMD. Classification of Obstructive Sleep Apnea (OSA) was determined based on oxygen desaturation index [ODI] with mild having values of 5\u201315 and moderate-to-severe &gt;15.<\/p>\n<h3 class=\"wp-block-heading\" id=\"ceo14428-sec-0003-title\">Results<\/h3>\n<p>A total of 225 participants were included with 76% having AMD, of which 42% had coexistent RPD. Of the AMD participants, 53% had early\/intermediate AMD, 30% had geographic atrophy (GA) and 17% had neovascular AMD (nAMD). Overall, mild or moderate-to-severe OSAwas not associated with an increased odds of having AMD nor AMD with RPD (<em>p<\/em>\u2009\u2265\u20090.180).<\/p>\n<p>However, moderate-to-severe OSA was associated with increased odds of having nAMD (odds ratio\u2009=\u20096.35; 95% confidence interval\u2009=\u20091.18 to 34.28;\u00a0<em>p<\/em>\u2009=\u20090.032), but not early\/intermediate AMD or GA, compared to controls (<em>p<\/em>\u2009\u2265\u20090.130). Mild OSA was not associated with differences in odds of having AMD of any severity (<em>p<\/em>\u2009\u2265\u20090.277).<\/p>\n<h3 class=\"wp-block-heading\" id=\"ceo14428-sec-0004-title\">Conclusions<\/h3>\n<p>There was an association between nocturnal hypoxia as measured by the ODI and nAMD. Hence, nocturnal hypoxia may be an under-appreciated important modifiable risk factor for nAMD.<\/p>\n<p> <!-- Form created by Optin Forms plugin by WPKube: create beautiful optin forms with ease! --> <!-- https:\/\/wpkube.com\/ --><!--optinforms-form5-container--> <!-- \/ Optin Forms --> <\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/neurosciencenews.com\/sleep-apnea-wet-amd-28180\/\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summary: A new study has linked moderate-to-severe obstructive sleep apnea (OSA), characterized by low oxygen levels overnight, with an increased risk of developing wet age-related macular degeneration (AMD). The research &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=133602\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-133602","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/133602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=133602"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/133602\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=133602"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=133602"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=133602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}