{"id":135827,"date":"2024-12-11T13:42:03","date_gmt":"2024-12-11T06:42:03","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=135827"},"modified":"2024-12-11T13:42:03","modified_gmt":"2024-12-11T06:42:03","slug":"alarm-as-medication-taken-by-thousands-of-brits-is-linked-to-dementia-in-new-research","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=135827","title":{"rendered":"Alarm as medication taken by thousands of Brits is linked to dementia in new research"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div itemprop=\"articleBody\">\n<p class=\"mol-para-with-font\">Medications for over-active bladders that are taken by hundreds-of-thousands of Brits could increase the risk of developing dementia, new research suggests.<\/p>\n<p class=\"mol-para-with-font\">The pills, called anticholinergics, work by reducing the activity of certain muscles to stop the bladder contracting.\u00a0<\/p>\n<p class=\"mol-para-with-font\">This helps stop the spasms that can cause incontinence and the need to urinate frequently.<\/p>\n<p class=\"mol-para-with-font\">But a new study on almost 1million Brits suggests some types of these medications can increase the risk of dementia by about third.\u00a0<\/p>\n<p class=\"mol-para-with-font\">British experts analysed the health records of just over 170,000 patients in England over the age of 55 with dementia and compared them to 800,000 patients without the memory robbing disorder.<\/p>\n<p class=\"mol-para-with-font\">Overall, the authors found taking an\u00a0anticholinergic was linked to an 18 per cent increased risk of dementia diagnosis.<\/p>\n<p class=\"mol-para-with-font\">However, they found the elevated risk to be slightly higher in men \u2014 22 per cent, compared to women at 16 per cent.<\/p>\n<p class=\"mol-para-with-font\">Some specific types of the drugs also carried a much higher risk.<\/p>\n<div class=\"artSplitter mol-img-group\" style=\"\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"> <img decoding=\"async\" id=\"i-8830d926616b53b2\" src=\"https:\/\/i.dailymail.co.uk\/1s\/2024\/12\/10\/15\/93001633-14177847-image-a-1_1733845055344.jpg\" height=\"423\" width=\"634\" alt=\"Medications for over-active bladders are taken by hundreds-of-thousands of Brits could increase the risk of getting dementia, new research suggests\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/> <\/div>\n<p> <noscript> <img loading=\"lazy\" decoding=\"async\" id=\"i-8830d926616b53b2\" src=\"https:\/\/i.dailymail.co.uk\/1s\/2024\/12\/10\/15\/93001633-14177847-image-a-1_1733845055344.jpg\" height=\"423\" width=\"634\" alt=\"Medications for over-active bladders are taken by hundreds-of-thousands of Brits could increase the risk of getting dementia, new research suggests\" class=\"blkBorder img-share\" \/> <\/noscript> <\/div>\n<p class=\"imageCaption\">Medications for over-active bladders are taken by hundreds-of-thousands of Brits could increase the risk of getting dementia, new research suggests<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">Those prescribed oxybutynin hydrochloride had a 31 per cent higher risk of dementia, and those on tolterodine tartrate had a 27 per cent increased risk.<\/p>\n<p class=\"mol-para-with-font\">The experts said their findings emphasised the need for medics to consider alternative treatments for overactive bladder in older patients.<\/p>\n<p class=\"mol-para-with-font\">NHS data suggests hundreds of thousands of prescriptions for these medications are doled out by the health service in England each month.<\/p>\n<p class=\"mol-para-with-font\">However, the authors, who published their research in the <a style=\"font-weight: bold;\" class=\"\" rel=\"nofollow noreferrer noopener\" target=\"_blank\" href=\"https:\/\/bmjmedicine.bmj.com\/content\/3\/1\/e000799#sec-20\">British Medical Journal<\/a>, found that some types of anticholinergics weren&#8217;t linked to an increased chance of dementia.\u00a0<\/p>\n<p class=\"mol-para-with-font\">These were darifenacin, fesoterodine fumarate, flavoxate hydrochloride, propiverine hydrochloride, and trospium chloride.\u00a0<\/p>\n<p class=\"mol-para-with-font\">The experts also analysed a non-anticholinergic drug called\u00a0mirabegron, which is also prescribed to patients with overactive bladders, but works using a different mechanism than\u00a0anticholinergics.<\/p>\n<p class=\"mol-para-with-font\">While the scientists did find some evidence of dementia links to this drug, they noted the data wasn&#8217;t clear, and further research is needed.\u00a0<\/p>\n<div class=\"artSplitter mol-img-group\" style=\"\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"> <img decoding=\"async\" id=\"i-ad6191edded8271d\" src=\"https:\/\/i.dailymail.co.uk\/1s\/2024\/12\/10\/15\/93001841-14177847-NHS_backed_data_source_OpenPrescribing_records_about_110_000_pre-a-14_1733845536861.jpg\" height=\"231\" width=\"634\" alt=\"NHS-backed data source OpenPrescribing records about 110,000 prescriptions of oxybutynin per month\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/> <\/div>\n<p> <noscript> <img loading=\"lazy\" decoding=\"async\" id=\"i-ad6191edded8271d\" src=\"https:\/\/i.dailymail.co.uk\/1s\/2024\/12\/10\/15\/93001841-14177847-NHS_backed_data_source_OpenPrescribing_records_about_110_000_pre-a-14_1733845536861.jpg\" height=\"231\" width=\"634\" alt=\"NHS-backed data source OpenPrescribing records about 110,000 prescriptions of oxybutynin per month\" class=\"blkBorder img-share\" \/> <\/noscript> <\/div>\n<p class=\"imageCaption\">NHS-backed data source OpenPrescribing records about 110,000 prescriptions of oxybutynin per month<\/p>\n<\/div>\n<p class=\"mol-para-with-font\">Concluding their report they said clinicians need to &#8216;take into account the possible long term risks and consequences of the available treatment options for an overactive bladder in older adults&#8217;.<\/p>\n<p class=\"mol-para-with-font\">Doctors should &#8216;consider prescribing alternative treatments that might be associated with a lower risk of dementia,&#8217; they added.<\/p>\n<p class=\"mol-para-with-font\">The study was based on an analysis of health data from\u00a0170,742 Brits over the age of 55 with dementia who had taken an anticholinergic drug or\u00a0mirabegron for three to 16 years before their dementia diagnosis.\u00a0<\/p>\n<p class=\"mol-para-with-font\">Each Brit with dementia was matched with a participant from an 800,000 strong control group in terms of their exact age, sex and GP practice in order to make a comparison.<\/p>\n<p class=\"mol-para-with-font\">The study had several limitations, the first of which is that data for exact dosage given to patients was lacking meaning the authors couldn&#8217;t fully explore if higher doses of some drugs led to an increased risk of dementia over time.<\/p>\n<p class=\"mol-para-with-font\">Another was the data relied on patient records which may have been unreliable or incomplete.\u00a0<\/p>\n<p class=\"mol-para-with-font\">The study isn&#8217;t the first to link some anticholinergics to increased dementia risk, although exactly how the drugs affect the brain isn&#8217;t fully understood.<\/p>\n<p class=\"mol-para-with-font\">Previous studies have highlighted\u00a0oxybutynin, sold under the brands\u00a0Aspire, Ditropan, Kentera, can be a<a style=\"font-weight: bold;\" target=\"_self\" class=\"\" href=\"https:\/\/www.dailymail.co.uk\/health\/article-4351754\/Bladder-drug-taken-thousands-linked-dementia.html\" rel=\"noopener\">\u00a0particular risk<\/a>\u00a0as it has a smaller molecule size than other types.<\/p>\n<div class=\"artSplitter mol-img-group\" style=\"\">\n<div class=\"mol-img\">\n<div class=\"image-wrap\"> <img decoding=\"async\" id=\"i-6af32be196b364ea\" src=\"https:\/\/i.dailymail.co.uk\/1s\/2024\/12\/10\/15\/70440883-14177847-Being_unable_to_learn_new_tasks_and_struggling_to_stay_focused_o-a-3_1733845124221.jpg\" height=\"393\" width=\"634\" alt=\"Being unable to learn new tasks and struggling to stay focused on a single task can be a sign of dementia\" class=\"blkBorder img-share\" style=\"max-width:100%\" loading=\"lazy\" \/> <\/div>\n<p> <noscript> <img loading=\"lazy\" decoding=\"async\" id=\"i-6af32be196b364ea\" src=\"https:\/\/i.dailymail.co.uk\/1s\/2024\/12\/10\/15\/70440883-14177847-Being_unable_to_learn_new_tasks_and_struggling_to_stay_focused_o-a-3_1733845124221.jpg\" height=\"393\" width=\"634\" alt=\"Being unable to learn new tasks and struggling to stay focused on a single task can be a sign of dementia\" class=\"blkBorder img-share\" \/> <\/noscript> <\/div>\n<p class=\"imageCaption\">Being unable to learn new tasks and struggling to stay focused on a single task can be a sign of dementia\u00a0<\/p>\n<\/div>\n<p><iframe data-xpmodule-iframe-resizable=\"\" scrolling=\"no\" name=\"xp-iframe-m4jip9iu9v6vof0cb0v\" class=\"iframe-creator \" src=\"https:\/\/i.dailymail.co.uk\/i\/html_modules\/2024\/07_JUL\/240731_Dementia_Factors\/index.html\" allow=\"clipboard-write\" height=\"200\" style=\"border: 0; width: 0; min-width: 100%; \" id=\"xp-iframe-m4jip9iu9v6vof0cb0v\"><\/p>\n<p>Your browser does not support iframes.<\/p>\n<p>    <\/iframe><\/p>\n<p class=\"mol-para-with-font\">This, experts say,\u00a0 enables it to penetrate deeper into the brain and have a stronger affect on the sensitive tissues there.\u00a0<\/p>\n<p class=\"mol-para-with-font\">NHS-backed data source OpenPrescribing records about 110,000 prescriptions of\u00a0oxybutynin per month at the cost to the taxpayer of just 15p per pill.<\/p>\n<p class=\"mol-para-with-font\">Dementia is an umbrella term used to describe a range of progressive disorders which impact memory, thinking and behaviour.<\/p>\n<p class=\"mol-para-with-font\">There are many types of dementia, with that linked to Alzheimer\u2019s disease being the most common.<\/p>\n<p class=\"mol-para-with-font\">Dementia is a growing problem in Britain due to an ageing population, with an almost a million people estimated to be living with the condition though this predicted to increase.<\/p>\n<p class=\"mol-para-with-font\">The disorder is thought to cost the country some \u00a340billion per year, a combination of health care costs and loss of income from people needing to take time off work to care for relatives.\u00a0<\/p>\n<p class=\"mol-para-with-font\">The new study comes just days after Brits were warned another medication, this time to manage acid reflux, <a style=\"font-weight: bold;\" target=\"_self\" class=\"\" href=\"https:\/\/www.dailymail.co.uk\/health\/article-14136667\/pharmacist-warning-omeprazole-acid-reflux-drugs-heartburn-dementia.html\" rel=\"noopener\">is also linked to dementia<\/a>.\u00a0<\/p>\n<\/div>\n<p><script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<br \/><div data-type=\"_mgwidget\" data-widget-id=\"1660802\">\r\n<\/div>\r\n<script>(function(w,q){w[q]=w[q]||[];w[q].push([\"_mgc.load\"])})(window,\"_mgq\");\r\n<\/script>\r\n<br \/>\n<br \/><a href=\"https:\/\/www.dailymail.co.uk\/health\/article-14177847\/medication-taken-thousands-Brits-linked-dementia.html\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Medications for over-active bladders that are taken by hundreds-of-thousands of Brits could increase the risk of developing dementia, new research suggests. The pills, called anticholinergics, work by reducing the activity &hellip; <a href=\"https:\/\/hotvideos24.online\/?p=135827\" class=\"more-link\">Read More<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-135827","post","type-post","status-publish","format-standard","hentry","category-health","entry"],"_links":{"self":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/135827","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=135827"}],"version-history":[{"count":0,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=\/wp\/v2\/posts\/135827\/revisions"}],"wp:attachment":[{"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=135827"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=135827"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hotvideos24.online\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=135827"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}