{"id":138424,"date":"2024-12-18T14:15:49","date_gmt":"2024-12-18T07:15:49","guid":{"rendered":"https:\/\/hotvideos24.online\/?p=138424"},"modified":"2024-12-18T14:15:49","modified_gmt":"2024-12-18T07:15:49","slug":"scientists-find-new-forms-of-life-inside-humans","status":"publish","type":"post","link":"https:\/\/hotvideos24.online\/?p=138424","title":{"rendered":"Scientists find new forms of life inside humans"},"content":{"rendered":"<p> <script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-3711241968723425\"\r\n     crossorigin=\"anonymous\"><\/script>\r\n<ins class=\"adsbygoogle\"\r\n     style=\"display:block\"\r\n     data-ad-format=\"fluid\"\r\n     data-ad-layout-key=\"-fb+5w+4e-db+86\"\r\n     data-ad-client=\"ca-pub-3711241968723425\"\r\n     data-ad-slot=\"7910942971\"><\/ins>\r\n<script>\r\n     (adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script><br \/>\n<\/p>\n<div>\n<p>Every time we think we\u2019re close to fully understanding the human body, something fresh and unexpected shows up. Recently, a team of researchers stumbled upon strange entities, or obelisks, living inside of <a href=\"https:\/\/www.earth.com\/news\/toxic-chemicals-from-food-production-pass-into-the-human-body\/\" target=\"_blank\" rel=\"noreferrer noopener\">human bodies<\/a> that had escaped notice until now.<\/p>\n<p>Their surprising presence challenges assumptions and raises pressing questions about what else might be lurking unseen inside us.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-hidden-presence\">Hidden presence<\/h2>\n<p>These new visitors appear smaller than the <a href=\"https:\/\/www.earth.com\/news\/ice-age-viruses-hold-clues-to-earth-past-future-climate-and-microbial-evolution\/\" target=\"_blank\" rel=\"noreferrer noopener\">viruses<\/a> most people learn about in basic biology classes. Rather than behaving like familiar microbes, they introduce themselves as something different.<\/p>\n<p>Their discovery came about when researchers began analyzing massive genetic libraries, searching for patterns that did not match any known organisms. <\/p>\n<p>This unusual find was led by Nobel Prize winner in Medicine <a href=\"https:\/\/profiles.stanford.edu\/andrew-fire\">Andrew Fire<\/a>, from <a href=\"https:\/\/www.stanford.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Stanford University<\/a>.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-calling-them-obelisks\">Calling them obelisks<\/h2>\n<p>What the researchers uncovered are entities they have chosen to call \u201cobelisks.\u201d They do not resemble typical life forms, and their name comes from their distinctive shape. <\/p>\n<p>\u201cThe more we look, the crazier we see,\u201d said <a href=\"https:\/\/www.med.unc.edu\/cellbiophysio\/directory\/mark-peifer-phd\/\">Mark Peifer<\/a>, a cell and developmental biologist at the <a href=\"https:\/\/www.northcarolina.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">University of North Carolina<\/a>.<\/p>\n<p>They resemble what scientists call viroids, which are infectious loops of <a href=\"https:\/\/www.earth.com\/news\/rna-world-unraveling-mysteries-life-origin\/\" target=\"_blank\" rel=\"noreferrer noopener\">RNA<\/a> known for their effects on plants. <\/p>\n<p>Obelisks share certain traits with these plant pathogens, yet they appear in human-associated bacteria. <\/p>\n<p>According to <a href=\"https:\/\/microbiology.osu.edu\/people\/sullivan.948\">Matthew Sullivan<\/a>, an integrative biologist at <a href=\"https:\/\/www.osu.edu\/\" target=\"_blank\" rel=\"noreferrer noopener\">Ohio State University<\/a>, the health implications for humans remain unclear.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-understanding-rna-the-basics\">Understanding RNA \u2014 the basics<\/h2>\n<p>RNA, or ribonucleic acid, is a vital molecule that plays several important roles in all living cells. Think of it as the messenger that helps turn the genetic instructions stored in DNA into the proteins that build and repair your body. <\/p>\n<p>Unlike DNA, which usually forms a double helix, RNA is typically single-stranded and can fold into different shapes to perform various functions. <\/p>\n<p>There are different types of RNA, such as messenger RNA (<a href=\"https:\/\/www.earth.com\/news\/covid-vaccines-linked-to-neurological-blood-and-heart-related-issues\/\" target=\"_blank\" rel=\"noreferrer noopener\">mRNA<\/a>), transfer RNA (<a href=\"https:\/\/www.earth.com\/news\/fathers-diet-impacts-the-health-of-his-future-children\/\" target=\"_blank\" rel=\"noreferrer noopener\">tRNA<\/a>), and ribosomal RNA (<a href=\"https:\/\/www.earth.com\/news\/molecular-fingerprints-could-be-key-to-early-cancer-detection\/\" target=\"_blank\" rel=\"noreferrer noopener\">rRNA<\/a>) which is a key component of ribosomes, the cell\u2019s protein factories.<\/p>\n<p>But RNA isn\u2019t just about making proteins \u2014 it also helps regulate how genes are expressed and can even act as a catalyst in certain chemical reactions. <\/p>\n<p>For example, some RNA molecules can turn genes on or off, controlling what proteins are made and when. This regulation is crucial for everything from development to responding to changes in your environment.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-strange-rna-loops\">Strange RNA loops<\/h2>\n<p><a href=\"https:\/\/www.earth.com\/news\/giant-viruses-found-in-yellowstones-hot-springs-are-1-5-billion-years-old\/\">Viruses<\/a> often have protective shells made of proteins. Obelisks seem to lack that familiar coat. Instead, they carry RNA instructions around in tiny loops.<\/p>\n<p>Unlike standard viruses, they do not appear to encode protein shells. These differences suggest that life\u2019s definitions might need some rethinking.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-obelisks-throughout-human-bodies\">Obelisks throughout human bodies<\/h2>\n<p>It is not just a single type of obelisk. Thousands of unique varieties have turned up when scientists comb through genetic datasets.<\/p>\n<p>Discoveries have emerged from multiple locations around the world, indicating that these intruders are not rare oddities tucked away in one place.<\/p>\n<p>Not only are these obelisks found far and wide, they also appear in different parts of the human body. They have cropped up in <a href=\"https:\/\/www.earth.com\/news\/bacteria-in-your-mouth-multiply-in-a-very-unique-way\/\">bacteria from the mouth<\/a> and in those dwelling in the intestinal tract.<\/p>\n<p>The genetic signatures hint that distinct types prefer particular regions. This suggests an intricate relationship with our internal ecosystems, though it is too soon to say what they are doing there.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-evolutionary-puzzles\">Evolutionary puzzles<\/h2>\n<p>Their unusual nature stirs questions about how viruses, viroids, and these newcomers might be related. <\/p>\n<p>A persistent puzzle has always been whether today\u2019s viruses originated from simpler <a href=\"https:\/\/www.earth.com\/news\/human-cells-communicate-with-each-other-through-rna\/\">RNA forms<\/a> or if they started out more complex and shed traits over time.<\/p>\n<p>Entities like obelisks add color to these debates, leaving scientists wondering how ancient these forms might be and how they took shape during the planet\u2019s biological history.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-categorizing-human-obelisks\">Categorizing human obelisks<\/h2>\n<p>Obelisks do not slide neatly into existing categories. They are not standard viruses, not classic bacteria, and not exactly viroids either.<\/p>\n<p>Their discovery hints that we may be missing entire classes of RNA-based life that challenge current textbooks. This complicates efforts to catalog and understand the full range of microbial life.<\/p>\n<p>This investigation involved scanning colossal gene catalogs derived from human-associated microbes. Researchers used new computational tools to spot circular <a href=\"https:\/\/www.earth.com\/news\/lifes-molecular-orientation-new-discovery-deepens-the-mystery\/\">RNA molecules<\/a>. <\/p>\n<p>These approaches required careful filtering to ensure what they found was not just random noise. The effort paid off, revealing a strange world that had gone unnoticed.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-a-fresh-perspective\">A fresh perspective<\/h2>\n<p>\u201cThis is one of the most exciting parts of being in this field right now,\u201d said <a href=\"https:\/\/biosciences.lbl.gov\/profiles\/simon-roux\/\" target=\"_blank\" rel=\"noreferrer noopener\">Simon Roux<\/a>, a computational biologist at the <a href=\"https:\/\/jgi.doe.gov\/\" target=\"_blank\" rel=\"noreferrer noopener\">DOE Joint Genome Institute<\/a> at Lawrence Berkeley National Laboratory.<\/p>\n<p>These sentiments reflect a general feeling among experts who are sifting through molecular data and finding surprises. <\/p>\n<p>The study that introduced obelisks was posted on January 21st on <em>bioRxiv<\/em>, sparking interest among scientists who study microbial communities.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-still-so-many-unknowns\">Still so many unknowns<\/h2>\n<p>While researchers piece together the story of obelisks, the potential impact on humans remains uncertain. They know these <a href=\"https:\/\/www.earth.com\/news\/rna-world-unraveling-mysteries-life-origin\/\">RNA circles<\/a> live inside bacterial cells that, in turn, inhabit our bodies.<\/p>\n<p>If these entities influence bacterial behavior, they could, by extension, shape aspects of our own biology. Nobody can say yet what the long-term implications will be.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-what-s-next-for-human-obelisks\">What\u2019s next for human obelisks?<\/h2>\n<p>The human body is more than organs and tissues; it is a crowded universe of tiny creatures, many of them strangers we have not fully met before.<\/p>\n<p>Obelisks may be just one example of what can happen when scientists look at genetic data in new ways. There could be more discoveries ahead, each one forcing us to adjust how we describe life and its building blocks.<\/p>\n<p>Until then, researchers continue to watch, learn, and puzzle over these miniature visitors that have managed to hide in plain sight.<\/p>\n<p>The full study was published in <a href=\"https:\/\/www.biorxiv.org\/\" target=\"_blank\" rel=\"noreferrer noopener\"><em>bioRxiv<\/em><\/a> and <a href=\"https:\/\/royalsocietypublishing.org\/journal\/rsos\" target=\"_blank\" rel=\"noreferrer noopener\"><em>Royal Society Open Science<\/em><\/a>. <\/p>\n<p>Current research on circular RNA:<\/p>\n<p>\u2014\u2013<\/p>\n<p>Like what you read?<a href=\"https:\/\/www.earth.com\/subscribe\/\"> Subscribe to our newsletter<\/a> for engaging articles, exclusive content, and the latest updates.\u00a0<\/p>\n<p>Check us out on<a href=\"https:\/\/www.earth.com\/earthsnap\/\"> EarthSnap<\/a>, a free app brought to you by<a href=\"https:\/\/www.earth.com\/author\/eralls\/\"> Eric Ralls<\/a> and Earth.com.<\/p>\n<p>\u2014\u2013<\/p>\n<\/div>\n<p><script>self.__next_f.push([1,\"d:[\\\"$\\\",\\\"html\\\",null,{\\\"lang\\\":\\\"en\\\",\\\"children\\\":[[\\\"$\\\",\\\"head\\\",null,{\\\"children\\\":[[\\\"$\\\",\\\"script\\\",null,{\\\"src\\\":\\\"https:\/\/cdn.onesignal.com\/sdks\/web\/v16\/OneSignalSDK.page.js\\\",\\\"defer\\\":true}],[\\\"$\\\",\\\"script\\\",null,{\\\"dangerouslySetInnerHTML\\\":{\\\"__html\\\":\\\"\\\\n                            window.OneSignalDeferred = window.OneSignalDeferred || [];\\\\n                            OneSignalDeferred.push(async function(OneSignal) {\\\\n                                await OneSignal.init({\\\\n                                    appId: 'a4c6022f-d31e-4424-bdf3-a381492e0291',\\\\n                                });\\\\n                            });\\\\n                        \\\"}}]]}],[\\\"$\\\",\\\"body\\\",null,{\\\"className\\\":\\\"__variable_55b985 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