Giants vs. Cowboys odds, prediction, time, spread: Thursday Night Football picks by NFL model on 42-22-run

The Dallas Cowboys will try to regain the dominance that saw them win the NFC East a year ago when they battle the division-rival New York Giants on Thursday Night Football. Dallas outscored New York, 89-17, in two games last season, including a 40-0 win on the Giants’ home field. The Cowboys (1-2), who fell behind big and could never catch up last Sunday in a 28-25 loss to the Baltimore Ravens, are looking for their sixth division title since 2014. The Giants (1-2), who registered their first win of the year with a 21-15 win at Cleveland in Week 3, are looking to reach the postseason for the second time in three years. They have not won a division title since 2011, the last time they won the Super Bowl.

Kickoff from MetLife Stadium in East Rutherford, N.J., is set for 8:15 p.m. ET. The Cowboys are 5.5-point favorites in the latest Giants vs. Cowboys odds, while the over/under for total points scored is 45.5. Before making any Cowboys vs. Giants picks, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 4 of the 2024 NFL season on an incredible 188-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 42-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.    

Now, the model has set its sights on Cowboys vs. Giants and just locked in its picks and NFL predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and NFL betting lines for the spread, money line and over/under for Giants vs. Cowboys: 

• Giants vs. Cowboys spread: Dallas -5.5
• Giants vs. Cowboys over/under: 45.5 points
• Giants vs. Cowboys money line: Dallas -261, New York Giants +213
• DAL: Cowboys are 5-5 on the road since the start of 2023
• NYG: Giants are 4-5 at MetLife Stadium since the beginning of last season
• Giants vs. Cowboys picks: See picks at SportsLine

Why you should back the Cowboys

Dallas kicker Brandon Aubrey made history in last Sunday’s loss to the Ravens when he converted a 65-yard field goal in the first quarter. It is the second-longest field goal in league history, trailing only Justin Tucker, who connected on a 66-yarder on Sept. 26, 2021. Aubrey, who hit on a 60-yard field goal on Dec. 10, 2023, is the eighth kicker in NFL history with multiple made field goals of at least 60 yards. For the season, he has connected on 10 field goals and five extra points for a team-high 35 points.

Defensively, linebacker Eric Kendricks has led the defense with a team-high 29 tackles, including 14 solo. He also has registered two sacks for eight years, and one tackle for loss. He has knocked down one pass and intercepted another. The 10-year veteran, a former second-rounder by the Minnesota Vikings in 2015, has registered 1,065 career tackles, including 672 solo, with 20.5 sacks, five forced fumbles and six fumble recoveries. See which team to pick here.

Why you should back the Giants

Sixth-year veteran quarterback Daniel Jones is back under center this season after missing 11 games a year ago due to injury. In three games, he has completed 59.6% of his passes for 600 yards and four touchdowns. He has been picked off twice and has an 80.6 rating. In 63 career games, all with the Giants, he has completed 64% of his passes for 13,112 yards and 66 touchdowns. He has thrown 42 interceptions and has a rating of 84.9.

Helping power the defense is safety Jason Pinnock. The fourth-year veteran, who began his career with the New York Jets, is in his third year with the Giants. He is third on the team with 18 tackles, including 12 solo, and is tied for the team lead with three sacks for 13 yards and has three tackles for loss. He has also broken up one pass. See which team to pick here.

How to make Cowboys vs. Giants picks

SportsLine’s model is leaning Under the total, projecting 44 points. It also says one side of the spread has all the value. You can only get the NFL model’s picks at SportsLine.

So who wins Cowboys vs. Giants on Thursday Night Football, and which side of the spread has all the value? Visit SportsLine now to see which side of the Cowboys vs. Giants spread to jump on, all from the advanced model that is up well over $7,000 on its NFL picks, and find out.